Extramedullary Multiple Myeloma Presenting as a Pituitary Mass Lesion

Dimopoulou, Catherine; Ormanns, Steffen; Eigenbrod, Sabina; Müller-Lisse, Ullrich; Emmerich, Bertold; Reincke, Martín

doi:10.1055/s-0032-1321810

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Based on the present study and previous publications (12,14), intrasellar plasmacytoma should be considered in differential diagnosis with non-functioning pituitary adenoma, particularly in patients exhibiting cranial nerve involvement (especially the abducens nerve) (8), preserved anterior pituitary function, and an aggressive sellar mass on imaging. The distinction between these two types of sellar lesions is of paramount importance for both therapeutic and prognostic reasons (4,14,15).…”

Section: Discussionmentioning

confidence: 99%

Non-Functional Pituitary Tumors: a Misleading Presentation of an Intrasellar Plasmacytoma

et al. 2019

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Intrasellar plasmacytoma is a rare pituitary tumor, which originates from monoclonal plasma cells in a single lesion. Knowledge of its features comes from case reports only. Here, we present an interesting case of a 77-year-old woman with a presumptive diagnosis of nonfunctioning pituitary adenoma, as based on both clinical and radiological examinations. Following endoscopic endonasal transsphenoidal surgery, the definitive diagnosis of intrasellar plasmacytoma was made by immunohistochemical analysis of the sellar mass. Intrasellar plasmacytoma is rare, but it should be evaluated in the differential diagnosis of a pituitary mass due to its different therapeutic approach and prognosis, since it can frequently progress to multiple myeloma.

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