Extramedullary hematopoiesis with spinal cord compression in β-thalassemia intermedia

Adrenal extramedullary hematopoiesis associated with beta-thalassemia trait in an adult woman: a case report and review of literature

“…On the other side, radiographic characteristics, growth, and patient concern should be considered before the decision for lesions between 4 and 6 cm. The tumor size for surgery and management algorithm are different in cases with paraspinal extramedullary hematopoiesis [27] , [28] .…”

Bulky extramedullary hematopoiesis is not a rare complication of congenital dyserythropoietic anemia

“…However, the alternative hypothesis that the bulks observed develop from heterotopic hemopoietic cells is not excluded and is supported by autopsy findings failing any continuity between the ribs and the paravertebral masses [10]. We did not observe compression of the spinal cord by a paravertebral mass, as described in thalassemia [11,12]. However, this may also occur in other forms of ineffective erythropoiesis and therefore this possibility should be included in the differential diagnosis of neurological deficits of the lower limbs in patients with CDA.…”

Compression médullaire par un foyer d’hématopoïèse périrachidien au cours d’une β-thalassémie intermédiaire

“…Il doit être évoqué devant des antécédents connus de thalassémie ou d'anémie chronique associés à une hépatosplénomégalie et / ou à des adénopathies [6]. Les radiographies standard montrent la présence de masses paravertébrales bien limitées, associées à des signes d'EMH comme l'élargissement des côtes et l'amincissement des travées osseuses, sans signes de destruction osseuse ni fracture [7]. L'IRM rachidienne et médullaire constitue l'examen de référence pour le diagnostic de l'EMH.…”