Extrakranielles Meningeom in der Glandula parotis

Abstract

Extracranial meningiomas of the head and neck region are very rare, although secondary extracranial meningiomas beside meningiomas of primary extracranial origin have also been described. Trauma, radiation and (uncommonly) metastatic spread have been associated with the pathogenesis of secondary extracranial meningiomas. We present a case of a 53-year-old patient who required six neurosurgical interventions because of a recurrent intracranial meningioma. Further surgery was required for tumor in the left parotid gland. Histological examination of this neoplasm showed an atypical meningotheliomatous meningioma. The patient is now 17 months after surgery and is free of local recurrences or metastases.

Comparative study of soft tissue perineurioma and meningioma using a five‐marker immunohistochemical panel

“…These cases are at higher risk of being misinterpreted as extracranial meningiomas, particularly if only EMA is used and perineurioma is not considered as a possibility. On the other hand, a rare subset of meningiomas present as cutaneous or subcutaneous masses in the head and neck region, and might thus be mistaken for perineuriomas . More recently, Vajtai et al .…”

Perineurioma of the parotid gland: first case report

“…Indeed, these 2 distinct entities may be indistinguishable on histologic grounds alone, particularly if the possibility of perineurioma is not considered. Thus, it is certainly possible that some of the previously reported ectopic meningiomas of salivary gland may have in fact been perineuriomas [1,15]. It is important to note that immunohistochemistry for perineurial markers is not reliable to make this distinction, as both perineurioma and meningioma may express EMA, claudin-1, and GLUT-1 [16,17].…”

“…The differential diagnosis of salivary gland perineurioma also encompasses a group of rare neoplasms, in particular, spindle cell myoepithelioma, SFT [14], extracranial meningioma [15], follicular dendritic cell tumor, and other rare lesions. In addition to morphological mimicry of perineurioma, such lesions (especially SFT, meningioma, and follicular dendritic cell tumor) may also express markers commonly detected in perineurioma (EMA or CD34), creating differential diagnostic uncertainty.…”