Extragenital endometriosis in the differential diagnosis of non-gynecological diseases

Lukac, Stefan; Schmid, Marinus; Pfister, Kerstin; Janni, Wolfgang; Schäffler, Henning; Dayan, Davut

doi:10.3238/arztebl.m2022.0176

Cited by 10 publications

(13 citation statements)

References 51 publications

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“…The diaphragm is the most common site of thoracic endometriosis. In abdominal wall endometriosis, painful nodules arise in scars from prior abdominal surgery [4]. Symptoms are nonspecific and vary according to the site of involvement, and they are usually abdominal or pelvic pain, nausea, vomiting, diarrhea, and rectal bleeding [7].…”

Section: Introductionmentioning

confidence: 99%

“…Gastrointestinal endometriosis is the most common form of extragenital endometriosis (EE). In nearly 90% of cases, it affects the rectum and sigmoid colon [ 4 ]. The small intestine follows, most commonly the ileum, in 7-12% of cases, and the appendix in 6-8% of cases [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

“…The diaphragm is the most common site of thoracic endometriosis. In abdominal wall endometriosis, painful nodules arise in scars from prior abdominal surgery [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

“…Endometriosis of the diaphragm may cause period-associated shoulder pain or catamenial pneumothorax. Endometriosis affecting a nerve often presents with sciatica [ 4 ]. Complete intestinal obstruction is not a common finding in patients with endometriosis [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

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Endometriosis in the Cecum: A Rare Clinical Entity

Verzoviti¹,

Kalliouris²,

Boptsi³

et al. 2023

Cureus

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Cecal endometriosis is uncommon and may mimic other tumors of the colon, making it difficult to safely diagnose preoperatively. We report a case of a 50-year-old female who was found to have a cecal lesion during an endoscopic examination, which was performed for the investigation of anemia. It was also confirmed by conducting a computed tomography (CT) scan. Due to the high possibility of this mass identification as a neoplasm, the patient underwent a laparoscopic right hemicolectomy with an extracorporeal side-to-side isoperistaltic anastomosis. However, the postoperative histological diagnosis of the mass was cecal endometriosis, as the histopathology report noted endometrial tissues in the submucosa and muscolaris propria of the ileocecal region. Endometriosis of the cecum is a rare manifestation and can often be misdiagnosed as a malignant tumor. Further research is required, concerning preoperative characteristics of bowel masses in women, in order to provide optimal operative treatment and avoid unnecessary invasive procedures.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The diaphragm is the most common site of thoracic endometriosis. In abdominal wall endometriosis, painful nodules arise in scars from prior abdominal surgery [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Endometriosis in the Cecum: A Rare Clinical Entity

Verzoviti¹,

Kalliouris²,

Boptsi³

et al. 2023

Cureus

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“…The majority of cases of central nervous endometriosis affect the conus medullaris and/or cauda equina, but lesions in the brain have also been described [ 11 ]. Accordingly, symptoms can vary and include dysmenorrhea, dyspareunia, dyschezia, dysuria, pelvic pain, bloating, nausea, vomiting, hematuria, irritable bladder syndrome, and neurological symptoms [ 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review

Elefante

Brancati

Oragvelidze

et al. 2022

JCM

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Endometriosis is a systemic medical condition characterized by endometrial tissue that is abnormally implanted in extrauterine sites, including the central nervous system. In this article, we reported the case of a patient with presumed cerebral endometriosis who was diagnosed with bipolar disorder and panic disorder and systematically reviewed the literature for previously reported neuropsychiatric symptoms in patients with cerebral and cerebellar endometriosis. The PubMed, Scopus, and Web of Science bibliographic databases were searched according to the PRISMA guidelines. Seven previous case reports were found and described. While neurological disturbances dominated the clinical picture in the cases retrieved from the literature, our patient represented the first case to show both neurological and psychiatric manifestations. Atypical features of bipolar disorder including chronic mood instability, mixed episodes, and excitatory interepisodic symptoms were highlighted. During the neuropsychological evaluation, a dysexecutive profile consistent with frontal lobe pathology was evidenced. We hypothesized that the course and features of the illness were largely influenced by the presence of documented brain lesions compatible with endometrial implants, especially in the frontal region. Accordingly, patients with endometriosis who exhibit neurological as well as mental symptoms should be investigated for cerebral lesions.

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Three‐dimensional model for improvement of endometriosis care (3D‐E)

Lukac,

Hancke,

Janni

et al. 2023

Intl J Gynecology & Obste

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ObjectiveEndometriosis affects approximately 10% of women of reproductive age and leads to significant morbidity and financial burden. Consequently, countries such as France and Germany are formulating strategies to combat endometriosis. In this study, we propose the implementation of our three‐dimensional model (3D‐E) to raise awareness about endometriosis and enhance timely diagnosis, treatment, and long‐term care for affected patients.MethodsBased on the adapted Six Sigma Principle and the modified recommendation of Sales et al. for implementing evidence‐based findings into a clinical routine, we first conducted a comprehensive investigation to identify risk factors leading to diagnostic delay of endometriosis. After identifying improvable factors, the applicable options were selected due to defined criteria such as integrability in the clinical routine, cost‐effectiveness, and evidence‐based‐principle. Finally, solutions feasible for health care providers were integrated and the 3D‐E model was established.ResultsSome of the main risk factors contributing to diagnostic delays are symptoms acceptance and misinterpreted symptoms, especially if presenting to nongynecologists in cases of extragenital endometriosis with atypical presentation. Therefore, we tried to sensitize colleagues (first dimension) with a review paper in Germany's largest medical journal and started an elective for medical students (second dimension) at our university. In order to involve additional health care professionals in endometriosis care (third dimension), we are preparing the concept of the EndoNurse.ConclusionThe 3D‐E model is a relatively low‐cost, comprehensive, and worldwide adaptable approach for facilitating knowledge transfer, sensitizing health care providers, and improving endometriosis diagnostics and therapy for patients with endometriosis who are in the center of the model.

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Extragenital endometriosis in the differential diagnosis of non-gynecological diseases

Cited by 10 publications

References 51 publications

Endometriosis in the Cecum: A Rare Clinical Entity

Endometriosis in the Cecum: A Rare Clinical Entity

Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review

Three‐dimensional model for improvement of endometriosis care (3D‐E)

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