Extracts of seaweeds as potential inhibitors of quorum sensing and bacterial growth

Carvalho, Ana Polycarpa; Batista, Daniela; Dobretsov, Sergey; Coutinho, Ricardo

doi:10.1007/s10811-016-1014-1

Cited by 32 publications

(14 citation statements)

References 70 publications

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“…Another investigation on the same species, collected from the intertidal region of the Arabian Sea and Bay of Bengal, has found the methanolic extract to have anti-quorum sensing activity (Jha et al 2013 ). Other seaweed species have also been shown to produce quorum-sensing inhibitors (Carvalho et al 2017 ). Members of the genus Laurencia (Ceramiales) are also known to be a rich source of halogenated secondary metabolites (Blunt et al 2009 ) and they continue to be source of new compounds.…”

Section: Antifouling Compounds From Macroalgaementioning

confidence: 99%

Minireview: algal natural compounds and extracts as antifoulants

2017

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Marine biofouling is a paramount phenomenon in the marine environment and causes serious problems to maritime industries worldwide. Marine algae are known to produce a wide variety of chemical compounds with antibacterial, antifungal, antialgal, and anti-macrofouling properties, inhibiting the settlement and growth of other marine fouling organisms. Significant investigations and progress have been made in this field in the last two decades and several antifouling extracts and compounds have been isolated from micro- and macroalgae. In this minireview, we have summarized and evaluated antifouling compounds isolated and identified from macroalgae and microalgae between January 2010 and June 2016. Future directions for their commercialization through metabolic engineering and industrial scale up have been discussed. Upon comparing biogeographical regions, investigations from Southeast Asian waters were found to be rather scarce. Thus, we have also discussed the need to conduct more chemical ecology based research in relatively less explored areas with high algal biodiversity like Southeast Asia.

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Section: Antifouling Compounds From Macroalgaementioning

confidence: 99%

Minireview: algal natural compounds and extracts as antifoulants

2017

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“…Macroalgae also show antifouling defence by different ways such as the use of chemical and physical defences (Burns et al 2003;da Gama et al 2014) or symbiotic relationships between epibionts (e.g., bacteria) (Satheesh et al 2016). Due to these chemical defence, macroalgae are one of the most important groups for natural product antifouling research (Nylund et al 2007;Hellio et al 2009;Viano et al 2009;Saha and Wahl 2013;Othmani et al 2016;Carvalho et al 2017;Salama et al 2017).…”

Section: Discussionmentioning

confidence: 99%

Antimicrofouling activities of marine macroalga Dictyota dichotoma from the Red Sea

Gadhi

El‐Sherbiny

Al-Sofynai

et al. 2019

Jour. Agri. & Mar. Scie.

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Introduction. Marine organisms produce a variety of secondary metabolites mainly for achieving the defence against the competitors and predators. These compounds could be used as natural product antifoulants for the management of biofouling growth on marine structures. Objectives. To understand the antifouling defence strategies of marine macroalgae collected from the Red Sea. Methodology. The macroalga Dictyota dichotoma was collected from the Obhur Creek of Red Sea, Saudi Arabia and extracted using methanol. Surface and total extraction methods were performed and tested against a bacterial strain isolated from the microfouling assemblage. Results. The extracts obtained from the macroalgal samples have strong antibacterial and antibiofilm activities against the bacterial strain isolated from the marine microfouling assemblage. The total extracts showed strong bacterial growth inhibitory activities in culture plate method. In microtitre plate assay, surface extract showed strong biofilm inhibitory activity. GC-MS analysis indicated considerable variations in the metabolic profile of the surface and total extracts. Conclusion. This study revealed the importance of surface-associated compounds in antifouling defence mechanism of the marine macroalgae.

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“…Several extracts and compounds derived from macroalga with the ability to inhibit quorum sensing have been reported. For example, Carvalho et al (2017) [ 231 ], reported that C. cervicornis extracts inhibited the growth of C. violaceum , due to the inhibition of the quorum sensing, since no killing effect was observed. A study conducted with P. gymnospora demonstrated that the a lpha-bisabolol obtained from this alga inhibited significantly the quorum sensing and biofilm formation of S. marcescens [ 232 ].…”

Section: Applicationsmentioning

confidence: 99%

Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications

et al. 2020

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In the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms. Macroalgae play a special role in the pursuit of new active molecules as they have been traditionally consumed and are known for their chemical and nutritional composition and their biological properties, including antimicrobial activity. Among the bioactive molecules of algae, proteins and peptides, polysaccharides, polyphenols, polyunsaturated fatty acids and pigments can be highlighted. However, for the complete obtaining and incorporation of these molecules, it is essential to achieve easy, profitable and sustainable recovery of these compounds. For this purpose, novel liquid–liquid and solid–liquid extraction techniques have been studied, such as supercritical, ultrasound, microwave, enzymatic, high pressure, accelerated solvent and intensity pulsed electric fields extraction techniques. Moreover, different applications have been proposed for these compounds, such as preservatives in the food or cosmetic industries, as antibiotics in the pharmaceutical industry, as antibiofilm, antifouling, coating in active packaging, prebiotics or in nanoparticles. This review presents the main antimicrobial potential of macroalgae, their specific bioactive compounds and novel green extraction technologies to efficiently extract them, with emphasis on the antibacterial and antifungal data and their applications.

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Extracts of seaweeds as potential inhibitors of quorum sensing and bacterial growth

Cited by 32 publications

References 70 publications

Minireview: algal natural compounds and extracts as antifoulants

Minireview: algal natural compounds and extracts as antifoulants

Antimicrofouling activities of marine macroalga Dictyota dichotoma from the Red Sea

Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications

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