Extractive spectrophotometric methods for the determination of doxepin hydrochloride in pharmaceutical preparations using titanium (IV) and iron (III) thiocyanate complexes

Misiuk, Wieslawa

doi:10.1016/j.farmac.2004.09.004

Cited by 20 publications

(12 citation statements)

References 22 publications

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“…Due to the formation of relatively stable complex, the dynamic balance between dissolution and reparation of passive film is likely to be destroyed by the small anions in solution such as Cl − , SCN − etc. [10,40,41] (see the stage 3 in Figure 6). The destruction of TiO 2 film results in the direct exposure of titanium substrate to solution.…”

Section: Discussionmentioning

confidence: 99%

Streptococcus Sanguis Biofilm Architecture and Its Influence on Titanium Corrosion in Enriched Artificial Saliva

et al. 2017

Materials

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Bacteria biofilm formation on metals is well-known, while biofilm architecture varies under different conditions. To date, few studies have determined the possible contribution to corrosion of titanium made by biofilm architecture. We investigated the interaction between the oral Streptococcus sanguis biofilm architecture and its influence on titanium corrosion in enriched artificial saliva using electrochemical methods and microscopic study. Patchy biofilms were observed on titanium surface after being immersed in solution containing S. sanguis. The thickness and size of the patchy biofilms increased with an increase of immersion time. The extensive pits were clearly observed by scanning electron microscopy, showing that adsorption of S. sanguis on titanium promoted the localized corrosion. The electrochemical results indicated that the corrosion rates were clearly accelerated in the presence of S. sanguis. The low icorr and high Rt in the first 48 h indicated that a typical passive behavior still remained. Our study showed that the pitting corrosion of titanium was mainly attributed to the formation of a self-catalytic corrosion cell by the co-effect of patchy biofilm and organic acid secreted by S. sanguis.

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Section: Discussionmentioning

confidence: 99%

Streptococcus Sanguis Biofilm Architecture and Its Influence on Titanium Corrosion in Enriched Artificial Saliva

et al. 2017

Materials

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“…[9][10][11][12][13][14][15][16] Quantitative analysis of the drugs applying extractive spectrophotometric methods is mainly founded on such factors as type of solvent extraction, nature of coordination agents, acidity of the solution, concentration of reagents, temperature, time of reaction and extraction.…”

Section: )mentioning

confidence: 99%

Sensitive Extractive Spectrophotometric Methods for the Determination of Nortriptyline Hydrochloride in Pharmaceutical Formulations

Misiuk

Tykocka

2007

CHEMICAL & PHARMACEUTICAL BULLETIN

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Nortriptyline (NOR) belongs to the family of tricyclic antidepressants, a group of drugs widely used for treating depressive diseases. Its chemical structure is shown in Fig. 1.Most existing methods for the determination of nortriptyline in bulk, pharmaceutical formulations and biological samples have been reviewed. 1) Among other methods described for the assay of this drug are direct UV-spectrophotometry, 2,3) derivatives spectrophotometry, 4,5) fluorimetry 6) and colourimetry. 7,8) The colourimetric methods involve ion association complex with dye-Light Green FCF at pH 5 and Orange II 7) at pH 2 or charge-transfer complex with 7,7,8,8-tetracyanoquinodimethane (TCQN). 8)Extractive spectrophotometric procedures are popular for their sensitivity in the assay of drugs and, therefore, ion-pair extractive spectrophotometry has received considerable attention for the quantitative determination of many pharmaceutical compounds. [9][10][11][12][13][14][15][16] Quantitative analysis of the drugs applying extractive spectrophotometric methods is mainly founded on such factors as type of solvent extraction, nature of coordination agents, acidity of the solution, concentration of reagents, temperature, time of reaction and extraction.Some methodological reports for the determination of nortriptyline 6,7,11,21,[25][26][27] using specrophotometry have been published. However, these methods have several disadvantages in terms of cost performance, consumption of time and essential equipment, difficult reaction conditions and procedures for determination of drugs.For example, De La Pena et al. 6) developed a fast kinetic method for the determination of nortriptyline in pharmaceutical preparations by use of photometric and fluorimetric detection. But the applied procedures required a temperature of 50°C for both types of detection. Obtained linear dynamic ranges of the drug determinations were too broad.Another method 21) was based on oxidation of imipramine and desipramine (drugs related to nortriptyline) with ammonium metavanadate. The method has been developed for determination of the drugs in the visible (VIS) range. However, the applied oxidizing agent cannot be used for determination of nortriptyline in the VIS range. The drug oxidation product is colourless and ammonium metavanadate is an unsuitable agent for its production.Oztunc et al. 8) have proposed a method for nortriptyline determination which exhibited disadvantages in terms of difficult reaction conditions. In this procedure maximum absorption was reached at 80°C and heating time of 10 min was recommended for maximum intensity colour development.Most of the proposed agents for spectrophotometric determination of nortriptyline and related drugs are unsatisfactory for different reasons, e.g., a long period for maximum intensity color development, lengthy and difficult procedure, lack Sensitive Extractive Spectrophotometric Methods for the Determination of Nortriptyline Hydrochloride in Pharmaceutical FormulationsWieslawa MISIUK* and Agnieszka TYKOCKA

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“…Recently Misiuk[44] studied the ion association compounds of doxepin (DX) with thiocyanate complexes of titanium (IV) and iron (III). The produced compounds were insoluble in water, but well soluble in some organic solvents.…”

Section: Spectrophotometric Methodsmentioning

confidence: 99%

“…These compositions are described in the literature[244344]. The absorption spectra of the compounds obtained in the UV/VIS and IR-region have been recorded.…”

Section: Structures Of Binary and Ternary Complexes Of Psychotropic Dmentioning

confidence: 99%

Spectroscopic and electrochemical analysis of psychotropic drugs

Puzanowska-Tarasiewicz

Misiuk

Mielech-Łukasiewicz

et al. 2009

Indian J Pharm Sci

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Psychotropic drugs are an important family of compounds from a medical point of view. Their application in therapy requires methods for the determination in pharmaceutical dosage forms and body fluids. Several methods for their analysis have been reported in the literature. Among the methods, spectrophotometric and electrochemical are very useful for the determination of the drugs. Some of the spectrophotometric methods are based on the formation of the binary and ternary compounds with complexes of metals. The formed compounds are sparingly soluble in water, but quantitatively extracted from aqueous phase into organic solvents and the extracts are intensely colored and stable for a few days. These complexes have been employed in pharmaceutical analysis. The electrochemical procedures are very useful in determination of the psychotropic substances in pharmaceutical preparations.

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Extractive spectrophotometric methods for the determination of doxepin hydrochloride in pharmaceutical preparations using titanium (IV) and iron (III) thiocyanate complexes

Cited by 20 publications

References 22 publications

Streptococcus Sanguis Biofilm Architecture and Its Influence on Titanium Corrosion in Enriched Artificial Saliva

Streptococcus Sanguis Biofilm Architecture and Its Influence on Titanium Corrosion in Enriched Artificial Saliva

Sensitive Extractive Spectrophotometric Methods for the Determination of Nortriptyline Hydrochloride in Pharmaceutical Formulations

Spectroscopic and electrochemical analysis of psychotropic drugs

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