Extractive Spectrophotometric Determinationsl Of Some Phenothiazines with Picric and Flavianic Acids

Tarasiewicz, M.; Ÿmicka, L. Ku

doi:10.1080/00032719608001445

Cited by 18 publications

(11 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They can lower the activity of dopamine in the central nervous system, and have wide clinical application [3]. Their molecular structures are similar as shown in Scheme 1, so is their electrochemical property.…”

Section: Introductionmentioning

confidence: 96%

“…Because of the importance of this class of compounds, a lot of work has been reported on their characterization and determination in dosage forms and biological fluids. The methods used for their study included electroanalysis [1,2], spectrophotometry [3][4][5], chemiluminescence [6] and HPLC [7] etc. That has been reviewed by Korpinsk et al [8].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Voltammetric Determination of Prochlorperazine and Ethopropazine Using a Gold Electrode Modified with Decanethiol SAM

Yang

Peng

Zhao

et al. 2003

Sensors

View full text Add to dashboard Cite

Abstract:The voltammetric behavior of prochlorperazine and ethopropazine at a decanethiol (DEC) self-assembled monolayer (SAM) modified gold electrode (DEC/Au) has been studied. It was observed that prochlorperazine exhibited an anodic peak at about 0.60 V (vs SCE), while ethopropazine exhibited two anodic peaks at about 0.49 V and 0.58 V on DEC/Au in pH 10 sodium carbonate buffer. This was due to their different electrochemical oxidation mechanisms. In this case, the oxidation of prochlorperazine and ethopropazine included one 2e step and two 1e steps, respectively. In the presence of some reductants such as ascorbic acid, the oxidation products of them can catalyze the oxidation of the reductants and thus make the peaks grow. In addition, it was found that the SAM structure became not so compact when prochlorperazine and ethopropazine were present, resulting from their permeating in the SAM. Various conditions were optimized for their determination. Under the selected conditions (i.e. 0.080 M pH 10 sodium carbonate buffer; scan rate: 100 mV/s; accumulation potential: -0.4 V or 0 V; accumulation time: 60 s), the peak currents were linear to prochlorperazine concentration in the ranges of 0.1~2.0 M and 5.0~50 M, and linear with ethopropazine in the ranges of 10 nM~0.1 M and 0.5~20 M. The RSD was 4.28% for 8 successive measurements of 1.0 M prochlorperazine. The influence of some coexistents was examined.

show abstract

Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Voltammetric Determination of Prochlorperazine and Ethopropazine Using a Gold Electrode Modified with Decanethiol SAM

Yang

Peng

Zhao

et al. 2003

Sensors

View full text Add to dashboard Cite

show abstract

“…These methods include; spectrophotometry [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18], spectrofluorimetry [19][20][21][22][23][24], titrimetry [25][26][27][28][29][30], chromatography [31][32][33][34][35][36][37][38][39][40][41][42], flow injection analysis [43][44][45][46][47], radio-immunoassay [48][49], electrochemical methods [50][51] and chemiluminescence methods [52]…”

Section: Introductionmentioning

confidence: 99%

A validated spectrofluorimetric method for determination of some psychoactive drugs

Mohamed

Hussein

et al. 2005

Journal of Pharmaceutical and Biomedical Analysis

View full text Add to dashboard Cite

“…Among them, the most frequently used ones to determine thioridazine hydrochloride are chromatographic, [12][13][14][15][16] spectrophotometric, [17][18][19][20][21] and voltamperometric [22][23][24][25] methods. Among them, the most frequently used ones to determine thioridazine hydrochloride are chromatographic, [12][13][14][15][16] spectrophotometric, [17][18][19][20][21] and voltamperometric [22][23][24][25] methods.…”

Section: Introductionmentioning

confidence: 99%

UV Derivative Spectrophotometric Study of the Photochemical Degradation of Thioridazine Hydrochloride

Karpińska

Sokół

2003

Journal of Trace and Microprobe Techniques

View full text Add to dashboard Cite

A rapid, selective, and accurate method, based on derivative spectra is proposed for the quantification of thioridazine hydrochloride in the presence of its main degradation product-thioridazine sulphoxide, and vice versa. The determination of thioridazine hydrochloride was made using the second order of derivative (Á ¼ 22 nm, third polynomial degree) at 280 nm, while the determination of its sulphoxide is possible by applying the first order derivative spectra (Á ¼ 22 nm, second polynomial degree) based on measurements of derivative height at 312 nm. The calibration graphs were linear up to 30 and 50 mg/mL for thioridazine and its sulphoxide, respectively. The limits of detection were 2.91 and 0.77 mg/mL. The elaborated method was applied successfully for determination of the photostability of thioridazine hydrochloride in aqueous solution and in solid phase.

show abstract

Extractive Spectrophotometric Determinationsl Of Some Phenothiazines with Picric and Flavianic Acids

Cited by 18 publications

References 9 publications

Voltammetric Determination of Prochlorperazine and Ethopropazine Using a Gold Electrode Modified with Decanethiol SAM

Voltammetric Determination of Prochlorperazine and Ethopropazine Using a Gold Electrode Modified with Decanethiol SAM

A validated spectrofluorimetric method for determination of some psychoactive drugs

UV Derivative Spectrophotometric Study of the Photochemical Degradation of Thioridazine Hydrochloride

Contact Info

Product

Resources

About