Extractive spectrophotometric determination of ceterizine HCl in pharmaceutical preparations

Gowda, Babu Giriya; Melwanki, Mahaveer B.; Seetharamappa, J.

doi:10.1016/s0731-7085(01)00395-8

Cited by 45 publications

(20 citation statements)

References 3 publications

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“…A high-performance liquid chromatography (HPLC) with ultraviolet detection (UV) is the most widely used technique (Macek et al, 1999;Choi et al, 2000a, b;Kim et al, 2005;Zaater et al, 2000;Moncrieff, 1992;Jelinska et al, 2000Jelinska et al, , 2001Paw et al, 2002;Arayne et al, 2005;Bajerski et al, 2005;El Walily et al, 1998;Jaber et al, 2004;Nagaralli et al, 2003;Likar et al, 2005;Rosseel and Lefebvre, 1991) or liquid chromatography with spectrometric detection (LC-MS/MS) (Gergov et al, 2001;Gupta et al, 2005;de Jager et al, 2002;Rudaz et al, 2003;Song et al, 2005;Tan et al, 2006). Previously published methods included also gas chromatography (GC) (Baltes et al, 1988), high-performance thin-layer chromatography (HPTLC) (Makhija and Vavia, 2001;Pandya et al, 1996), electrooxidation (Güngör, 2004), spectrophotometric (El Walily et al, 1998;Mahgoub et al, 2003;Gowda et al, 2001;Basavaiah and Charan, 2002;Basavaiah et al, 1999;Gazy et al, 2002), titrimetric technique (Basavaiah and Charan, 2002) for cetirizine determination and assay based on cetirizine-tetraphenylborate ion-pair analysis (Shoukry et al, 1999). However, most of these procedures are time-consuming, not specific or selective enough.…”

Section: Introductionmentioning

confidence: 99%

“…However, most of these procedures are time-consuming, not specific or selective enough. A literature survey reveals that the majority of the papers describe the measurement in pharmaceutical formulations (Jelinska et al, 2000(Jelinska et al, , 2001Paw et al, 2002;Arayne et al, 2005;Bajerski et al, 2005;El Walily et al, 1998;Jaber et al, 2004;Nagaralli et al, 2003;Likar et al, 2005;Rudaz et al, 2003;Makhija et al, 2001;Güngör, 2004;Mahgoub et al, 2003;Gowda et al, 2001;Basavaiah and Charan, 2002;Basavaiah et al, 1999;Gazy et al, 2002;Shoukry et al, 1999). There are only a few reports on the cetirizine analysis in human (Macek et al, 1999;Kim et al, 2005;Nagaralli et al, 2003;de Jager et al, 2002;Song et al, 2005;Tan et al, 2006;Baltes et al, 1988;Pandya et al, 1996) or animal plasma samples (Choi et al, 2000a;Gupta et al, 2005), which have been based on HPLC following some form of liquid-liquid extraction (LLE) (Macek et al, 1999;Choi et al, 2000a;Kim et al, 2005;Nagaralli et al, 2003;Gupta et al, 2005;de Jager et al, 2002;Tan et al, 2006) or solidphase extraction (SPE) (Song et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

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Comparison of HPLC and CE methods for the determination of cetirizine dihydrochloride in human plasma samples

Kowalski

Plenis

2007

Biomedical Chromatography

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Two methods, capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC), for analysis of cetirizine dihydrochloride in small sample volumes of human plasma were compared. The CE and HPLC assays were developed and validated by analyzing a series of plasma samples containing cetirizine dihydrochloride in different concentrations using these two methods. The extraction procedure is simple and no complicated purification steps or derivatization are required. The analysis time in the HPLC method was shorter than that in the CE method, but solvent consumption was considerably lower in the CE method. The calibration curve was linear to at least 10-1000 ng/mL both for CE and HPLC with r(2) = 0.9993 and r(2) = 0.9994, respectively. The detection limits for cetirizine dihydrochloride were 3 and 5 ng/mL with CE and HPLC (a UV detector was applied in the both cases), respectively. Both methods were selective, robust and specific, allowing reliable quantification of cetirizine dihydrochloride, and could be useful for clinical and biomedical investigations.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of HPLC and CE methods for the determination of cetirizine dihydrochloride in human plasma samples

Kowalski

Plenis

2007

Biomedical Chromatography

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“…Year 2016 | Volume 4 | Issue 1 | Page [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] Scientific, UK. A centrifuge Model 90-1 with speed 50000 rpm (USA) was used to carry out for the spiked plasma samples.…”

Section: Canadian Chemical Transactionsmentioning

confidence: 99%

“…The spectrophotometric method is simpler, rapid, sensitive, selective and inexpensive. Spectrophotometric methods were reported [16,17] and by extraction [18,19].Bromocressol green (BCG), bromophenol blue (BPB) and bromothymol blue (BTB) are known to yield an ion pair complex, which are applied in the determination of many pharmaceutical compounds [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36].…”

Section: Introductionmentioning

confidence: 99%

Extractive-Spectrophotometric Methods for Determination of Alzheimer’s Drug in Pharmaceutical Formulations and in Biological Samples Using Sulphonphthalein Acid Dyes

2016

Can Chem Trans

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A simple, accurate and highly sensitive spectrophotometric methods are proposed for the rapid and accurate determination of Memantine HCl (MEM) using Bromophenol blue (BPB), Bromocressol purple (BCP) and Methyl orange (MO). The developed methods involve formation of stable yellow colored chloroform extractable ion-associate complexes of the amino derivative (basic nitrogen) of the MEM with three sulphonphthalein acid dyes, namely; BPB, BCP and MO, in phthalate buffer of pH range (3.0-3.8). The ion-associates exhibit absorption maxima at 415, 410 and 422 nm for BPB, BCP and MO, respectively. MEM can be determined up to 1.1-12.5, 0.8-13.1 and 0.6-14 µg/mL, respectively. The effect of optimum conditions via pH, reagent concentration, time, and solvent were studied. The low relative standard deviation values indicate good precision and high recovery values. These methods have been successfully applied for the assay of MEM in pharmaceutical formulations. Statistical comparison of the results with the reference method shows excellent agreement and indicates no significant difference in accuracy and precision.

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“…At a specific pH, the ion-pair, which is immiscible with water is extracted into an organic solvent and the concentration of it is determined spectrophotometrically [25][26][27][28]. The ion-pair extraction technique has some difficulties and inaccuracies arising from incomplete extraction or the formation of emulsions between the organic solvent and the basic compound, containing solution.…”

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confidence: 99%

Simple and sensitive spectrophotometric methods for the determination of acebutolol hydrochloride in bulk sample and pharmaceutical preparations

et al. 2008

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A direct, extraction-free spectrophotometric method has been developed for the determination of acebutolol hydrochloride (ABH) in pharmaceutical preparations. The method is based on ionpair complex formation between the drug and two acidic dyes (sulphonaphthalein) namely bromocresol green (BCG) and bromothymol blue (BTB). Conformity to Beer’s law enabled the assay of the drug in the range of 0.5-13.8 μg mL-1 with BCG and 1.8-15.9 μg mL-1 with BTB. Compared with a reference method, the results obtained were of equal accuracy and precision. In addition, these methods were also found to be specific for the analysis of acebutolol hydrochloride in the presence of excipients, which are co-formulated in the drug.

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Extractive spectrophotometric determination of ceterizine HCl in pharmaceutical preparations

Cited by 45 publications

References 3 publications

Comparison of HPLC and CE methods for the determination of cetirizine dihydrochloride in human plasma samples

Comparison of HPLC and CE methods for the determination of cetirizine dihydrochloride in human plasma samples

Extractive-Spectrophotometric Methods for Determination of Alzheimer’s Drug in Pharmaceutical Formulations and in Biological Samples Using Sulphonphthalein Acid Dyes

Simple and sensitive spectrophotometric methods for the determination of acebutolol hydrochloride in bulk sample and pharmaceutical preparations

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