Extractive fermentation with non-ionic surfactants to enhance butanol production

4. Introduction to bioconversion and downstream processing: principles and process examples

“…Many screenings have been performed to find suitable extractants among alcohols, alkanes, esters, different oils, as well as surfactants, ILs, and supercritical carbon dioxide [54][55][56][57][58][59][60]. The most common extractants for butanol that fulfills many screening criteria are dodecanol and oleyl alcohol.…”

Quest for sustainable bio-production and recovery of butanol as a promising solution to fossil fuel

“…Surfactants are normally classified by the nature of their head group as cationic, anionic, non-ionic and dual charge. Dhamole et al (2012) tested the biocompatibility of different non-ionic surfactants (Triton X 114, L64, L62LF, L61 and L62) and found that surfactant L62 could be considered as a potential extractant because it did not affect the yield and productivity of fermentation [79]. In this case, non-ionic surfactants increase ABE solvent biocompatibility with bacteria by means of cloud-point extraction [145].…”

Efficient acetone–butanol–ethanol (ABE) production by a butanol-tolerant mutant of Clostridium beijerinckii in a fermentation–pervaporation coupled process

“…However, one of the major obstacles limiting the economic viability of ABE fermentation is the low butanol concentration caused by butanol inhibition. Since butanol producing strains cannot tolerate more than 2% butanol [24], simultaneous removal of solvents from fermentation broth has been employed to relieve product inhibition [5,7,28]. Among all the in situ removal techniques, pervaporation is a separation process where a binary or multi-component liquid mixture is separated by partial vaporization through a membrane and is regarded as a promising process for separating ABE solvents [15].…”