Extraction, structure characterization and biological activity determination of (S)-(-)-palasonin from Butea monosperma (Lam.) Kuntze seeds

Fan, Qiqi; Li, Xinyu; Wei, Chunqi; Wang, Pei; Sun, Hong; Zheng, Sisi; Li, Yifan; Tian, Zhen; Liu, Jiyuan; Zhang, Yalin

doi:10.1016/j.indcrop.2022.115393

Cited by 6 publications

(10 citation statements)

References 49 publications

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“…(S)-(−)-palasonin has the potential to become a pesticide resistance management agent of P. xylostella, which can be used in a comprehensive management strategy. However, we noticed that field strains without exposure to (S)-(−)-palasonin still produced low levels of resistance, with a resistance ratio of 9.47-fold [11]. This suggests that there may be some cross-resistance between (S)-(−)-palasonin and other insecticides.…”

Section: Introductionmentioning

confidence: 83%

Glutathione S-Transferase May Contribute to the Detoxification of (S)-(−)-Palasonin in Plutella xylostella (L.) via Direct Metabolism

Fan

Liu

et al. 2022

Insects

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The control of P. xylostella primarily involves chemical insecticides, but overuse has brought about many negative effects. Our previous study reported that (S)-(−)-palasonin (PLN) is a plant-derived active substance with significant insecticidal activity against P. xylostella. However, we noticed a possible cross-resistance between (S)-(−)-palasonin and other insecticides which may be related to metabolic detoxification. In order to further explore the detoxification effect of detoxification enzymes on (S)-(−)-palasonin in P. xylostella, the effects of (S)-(−)-palasonin on enzyme activity and transcription level were determined, and the detoxification and metabolism of GSTs on (S)-(−)-palasonin were studied by in vitro inhibition and metabolism experiments. During this study, GST enzyme activity was significantly increased in P. xylostella after (S)-(−)-palasonin treatment. The expression levels of 19 GSTs genes were significantly increased whereas the expression levels of 1 gene decreased. Furthermore, (S)-(−)-palasonin is shown to be stabilized with GSTs and metabolized GSTs (GSTd1, GSTd2, GSTs1 and GSTs2) in vitro, with the highest metabolic rate of 80.59% for GSTs1. This study advances the beneficial utilization of (S)-(−)-palasonin as a botanical pesticide to control P. xylostella in the field.

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Section: Introductionmentioning

confidence: 83%

Glutathione S-Transferase May Contribute to the Detoxification of (S)-(−)-Palasonin in Plutella xylostella (L.) via Direct Metabolism

Fan

Liu

et al. 2022

Insects

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“…Flower, leaf, bark, and root extracts of B. monosperma showed insecticidal activity [105] against several crop pests. [106,107] Its methanolic seed extract is also found active against dengue vector, Aedes aegypti.…”

Section: Insecticidal Activitiesmentioning

confidence: 99%

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2022

IJGP

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The present review article explains phytochemistry, biological effects, and therapeutic uses of Butea monosperma and its associating species. This plant possesses great esthetic, medicinal, and therapeutic value in India. Palash is mentioned in holy Indian spiritual texts and has a long traditional use in Ayurvedic medicines. Its leaf decoction is used in the treatment of leukorrhea, diabetes, and for eye diseases. Flower, stem bark, root bark, and leaves possess diverse chemical constituents such as butrin, isobutrin, and isocoreopsin which showed very wide range of biological activities such as antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hepatoprotective, anti-gout activity, anti-inflammatory activity, ameliorative activity, anti-obese activity, anti-hyperglycemic, antinociceptive, anti-peroxidative anti-hepatotoxic, anthelmintic, chemopreventive, and hepatoprotective activity. Plant contains nutritive contents as fat 3.1, fiber 2.10, protein 16.87, and carbohydrate 75 (% per 100 g) and physiological important minerals such as Fe, Mn, Zn, Mg, and calcium. Plant flowers are good source of color which is traditionally used in religious rituals.

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“…The role of chemical insecticides in the management of these pests was indisputable; however, the extensive and irrational use of chemical agrochemicals has resulted in increasing resistances and environmental problems [6][7][8]. Cantharidin and (S)-(-)-palasonin showed different toxicity to P. xylostella, with median lethal concentrations, and quinolizidine alkaloids and neem-based products exhibited moderate acaricidal activities against T. urticae [9][10][11]. Therefore, the research and development of potential pesticide alternatives from bioactive plant natural products has received much attention in recent years [12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Exploration of Synergistic Pesticidal Activities, Control Effects and Toxicology Study of a Monoterpene Essential Oil with Two Natural Alkaloids

Fang

et al. 2023

Toxins

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With the increasing development of pest resistances, it is not easy to achieve satisfactory control effects by using only one agrochemical. Additionally, although the alkaloid matrine (MT) isolated from Sophora flavescens is now utilized as a botanical pesticide in China, in fact, its pesticidal activities are much lower in magnitude than those of commercially agrochemicals. To improve its pesticidal activities, here, the joint pesticidal effects of MT with another alkaloid oxymatrine (OMT) (isolated from S. flavescens) and the monoterpene essential oil 1,8-cineole (CN) (isolated from the eucalyptus leaves) were investigated in the laboratory and greenhouse conditions. Moreover, their toxicological properties were also studied. Against Plutella xylostella, when the mass ratio of MT and OMT was 8/2, good larvicidal activity was obtained; against Tetranychus urticae, when the mass ratio of MT and OMT was 3/7, good acaricidal activity was obtained. Especially when MT and OMT were combined with CN, the significant synergistic effects were observed: against P. xylostella, the co-toxicity coefficient (CTC) of MT/OMT (8/2)/CN was 213; against T. urticae, the CTC of MT/OMT (3/7)/CN was 252. Moreover, the activity changes over time of two detoxification enzymes, carboxylesterase (CarE) and glutathione S-transferase (GST) of P. xylostella treated with MT/OMT (8/2)/CN, were observed. In addition, by scanning electron microscope (SEM), the toxicological study suggested that the acaricidal activity of MT/OMT (3/7)/CN may be related to the damage of the cuticle layer crest of T. urticae.

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Extraction, structure characterization and biological activity determination of (S)-(-)-palasonin from Butea monosperma (Lam.) Kuntze seeds

Cited by 6 publications

References 49 publications

Glutathione S-Transferase May Contribute to the Detoxification of (S)-(−)-Palasonin in Plutella xylostella (L.) via Direct Metabolism

Glutathione S-Transferase May Contribute to the Detoxification of (S)-(−)-Palasonin in Plutella xylostella (L.) via Direct Metabolism

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Exploration of Synergistic Pesticidal Activities, Control Effects and Toxicology Study of a Monoterpene Essential Oil with Two Natural Alkaloids

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