Extraction socket preservation using a collagen plug combined withplatelet-rich plasma (PRP): A comparative clinico-radiographic study

Abstract

Background. Alveolar bone remodeling after tooth loss results in reduced ridge dimensions in horizontaland vertical planes. To prevent this, various authors have proposed different ridge preservationtechniques. A collagen plug is a novel material that has shown promising results in preserving thealveolar bone. PRP has also yielded favorable outcomes in wound healing and promoted osteoinductionand osteoconduction Methods. Thirty patients of both sexes with an age range of 30–18 years requiring bilateral extractionof teeth with similar tooth root anatomy in the maxilla or mandible were included in the study. Theextraction of teeth was carried out atraumatically. The patients’ arches were randomly divided andlabeled as the test or control sides. Bone width was measured on both sides. A collagen plug, with PRP,was placed, and the extraction socket was sutured on the test side. The control side was just sutured. Abaseline RVG was taken to record the apico-coronal height. The patients were recalled after 10 days forsuture removal and evaluation of wound healing. Parameters were re-evaluated at three and six monthspostoperatively. The data were subjected to t-test and one-way ANOVA. Results. The height of the crestal bone on the grafted side was more when compared to the non-graftedside three and six months after tooth extractions, and the difference was statically significant (P<0.001).No statistically significant difference was seen in the width of the alveolar bone three and six monthsafter tooth extraction (P>0.05). Conclusion. Collagen and PRP provided reasonable socket preservation as simple and inexpensiveoptions as compared to other materials.

Clinical Finding of Inert Collagen Sponge Saturated by Remineralizing Solution from Eggshell Powder versus Ca-OH in Indirect Pulp Capping Measured by Cone Beam Computed Tomography Radiograph

“…Development of sterile inert type I collagen sponge, of fish-origin like kolspon had been successfully used in many studies including that one; due to its biocompatibility and good absorbing characteristics. Those findings were in agreement with Fouda TA, et al; 2015 and Punde P, et al; 2020 (25,26) .…”

The Effect of Coenzyme Q10/Collagen Hydrogel on Bone Regeneration in Extraction Socket Prior to Implant Placement in Type II Diabetic Patients: A Randomized Controlled Clinical Trial

“…Extraction of teeth is common in Oral and Maxillofacial Surgery due extensive carious lesions, periapical pathology, or fractured crown or root in case of trauma or chronic periodontitis [ 35 ]. Many medical conditions may alter the healing after dental extraction as diabetes mellitus which is a pandemic metabolic disease associated with several complications, such as decreased bone remodeling and lowered levels of circulating biochemical bone markers, as well as reduction in the bone density [ 36 , 37 ].…”

Do autologous platelet concentrates (APCs) have a role in intra‐oral bone regeneration? A critical review of clinical guidelines on decision‐making process

“…Therefore, its application has become very limited. 74,75,150 PRGF has shown to be effective, 77,80 although some studies could not find any difference with unassisted healing. 76 A series of studies supported the use of L-PRF for ARP, not only accelerating soft tissue healing, 84,[86][87][88] but also limiting alveolar ridge resorption.…”

“…Two RCTs evaluated the use of PRP for ridge preservation 74,75 . Alissa et al 74 reported less pain, better soft tissue healing, and a denser trabecular bone pattern when PRP was compared to unassisted healing.…”