“…While modifier such as methanol can be added to enhance the selectivity and polarity of the fluid [1]. SFE has successfully been conducted on the extraction of interest and bioactive compounds from palm fatty acid [2], cardoon [3], peppermint [4], pitanga fruits [5], peach [6], dandelion leaves [7], abajeru [8], guava seeds [9], coffee beans [10], neem seeds [11], horsetail [12], jatropha seeds [13], garlic flakes [14], tomato [15], Mucuna seeds, [16], vanilla [17], celery seeds [18], paprika [19], hemp seed [20], and coconut flesh [21].…”