Extraction of ursolic acid from Ocimum sanctum by ultrasound: Process intensification and kinetic studies

Vetal, Mangesh D.; Lade, Vikesh G.; Rathod, Virendra K.

doi:10.1016/j.cep.2013.01.011

Cited by 111 publications

(53 citation statements)

References 36 publications

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“…This means that an increase in the temperature will affect the initial extraction rate of the batch extraction process more than in the case of UAE. Similar results are also reported by Vetal et al (2013) for the extraction of ursolic acid from Ocimum sanctum by ultrasound.…”

Section: The Effect Of Temperature On the Peleg's Rate Constantsupporting

confidence: 78%

KINETICS OF ULTRASOUND ASSISTED EXTRACTION OF WEDELOLACTONE FROM Eclipta alba

Charpe

Rathod

2016

Braz. J. Chem. Eng.

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-Ultrasound assisted extraction of wedelolactone, a major coumestan present in Eclipta alba, is investigated in the present work.Various process parameters such as type of solvent, power, solvent to solid ratio and extraction temperature, which affect the extraction yield, are optimized. In the ultrasound-assisted extraction with final optimized conditions, i.e., methanol as solvent, 170 W power, 60:1 solvent to solid ratio, 50 °C temperature and 60% duty cycle, amaximum extraction yieldof 0.62 mg/g is obtained in 45 minutes. The kinetic model (Peleg's model) has been used for the prediction of the yield of wedelolactone in the extract at a given time for all experimental conditions. The values of predicted yields show good agreement with the experimental data for all parameters, i.e., power, solvent to solid ratio and temperature. The extraction of wedelolactone from Eclipta alba is also carried out by conventional extraction methods, i.e., Soxhlet and batch extraction. Ultrasound-assisted extraction gives higher extraction yield in less time as compared to batch extraction (0.41 mg/g in 90 min) and Soxhlet extraction(0.7 mg/g in 360 min). The ultrasound-assisted extraction of wedelolactone from Eclipta alba is an effective way of extraction with the advantages of lower time and higher extraction.

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Section: The Effect Of Temperature On the Peleg's Rate Constantsupporting

confidence: 78%

KINETICS OF ULTRASOUND ASSISTED EXTRACTION OF WEDELOLACTONE FROM Eclipta alba

Charpe

Rathod

2016

Braz. J. Chem. Eng.

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“…Yet, R L/S of 36.2 mL g −1 has also been reported [15]. It should be stressed that optima R L/S determined for polyphenol extraction with conventional solvents may reach up to 100-120 mL g −1 [20,21], but such high values have never been predicted for polyphenol extraction with LTTMs. As pointed out earlier, a minimum R L/S is always required for sufficient mixing, which would allow for attaining appropriate diffusivity and hence increased extraction yield.…”

mentioning

confidence: 99%

“…Yet, RL/S of 36.2 mL g −1 has also been reported [15]. It should be stressed that optima RL/S determined for polyphenol extraction with conventional solvents may reach up to 100-120 mL g −1 [20,21], but such With respect to C LTTM , it has been suggested that the amount of water required depends on the polarity of the solute (polyphenols), with flavonoid glycosides, such as rutin, being more soluble in LTTMs with a higher water proportion, compared with its aglycone quercetin [12]. On such a ground, it has been supported that the extraction of more polar compounds may require LTTMs with higher water analogy [13].…”

mentioning

confidence: 99%

Ultrasound-Assisted Extraction of Polyphenolic Antioxidants from Olive (Olea europaea) Leaves Using a Novel Glycerol/Sodium-Potassium Tartrate Low-Transition Temperature Mixture (LTTM)

et al. 2017

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Abstract:Olive leaves (OLL) represent a major waste generated during the production of olive oil, but there is a great potential for their valorization, because they provide important content in polyphenolic phytochemicals, which possess several bioactivities. In spite of the high number of studies dealing with polyphenol recovery from olive leaves, green processes involving environmentally benign solvents are scarce. In this study, a novel renewable natural low-transition temperature mixture (LTTM), composed of glycerol and sodium-potassium tartrate, was tested for its efficient ability to extract polyphenolic substances from OLL. The extraction process was optimised by using response surface methodology and the maximum yield in total polyphenols was 26.75 ± 3.22 mg caffeic acid equivalents per g dry weight, achieved with 50% (v/v) aqueous LTTM, liquid-to-solid ratio of 45 mL g −1 and at 73 • C. The LTTM was proven to be equally effective with 60% aqueous methanol, but it displayed inferior antioxidant properties. Liquid chromatography-diode array-mass spectrometry analyses revealed no significant qualitative differences between the LTTM and the aqueous methanolic extract.

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“…Therefore, it can be concluded that ultrasound assisted reaction is faster and requires less time in comparison of conventional stirring method. trasound assisted hydroxylation with 15 hydrogen peroxide was found to be 15 Gardner units as against 18 Gardner units for crude soy lecithin which was shown in Table 2. Ultrasound assisted hydroxylation reaction was greatly accelerated using lactic acid 3 , wt/wt of CSL and hydrogen peroxide 15 , v/wt of CSL at 50 with100 W power and 70 duty cycle as compared to conventional method.…”

Section: Comparison Of Ultrasonic Irradiation With Conventionalmentioning

confidence: 99%

“…This increase in conversion with increase in temperature was mainly attributed to increase in miscibility of n-hexane in CSL and extent of cavitation at different temperature. Also the diffusion phenomenon is dominant at low temperature owing to high cavitation intensity as at low temperature rate of bubble generation is low but they collapse with high intensity 18 . Thus, the mass transport of the reactants on the catalytic sites is high.…”

Section: Effect Of the Lactic Acid Loadingmentioning

confidence: 99%