Extraction of phytochemicals with health benefit from Peperomia pellucida (L.) Kunth through liquid-liquid partitioning

Ho, Keat Lam; Tan, Chung Ghuan; Yong, Phaik Har; Wang, Chee Woon; Lim, Siew‐Huah; Kuppusamy, Umah Rani; Ngo, Chek Tung; Massawe, Festo; Ng, Zhi Xiang

doi:10.1016/j.jarmap.2022.100392

“…If we compare the obtained results through standard IC 50 values, the values obtained in our study for acarbose were insignificantly lower than the ones reported previously. 53 These results indicated that our extracts do not inhibit the activity of α-amylase, but the activity of α-glucosidase was substantial for further experimental design of our research. Recently, α-amylase has been found to play a significant role in the neuroinflammation associated with Alzheimer's disease.…”

Section: Food and Functionmentioning

confidence: 73%

The chemical profiling and assessment of antioxidative, antidiabetic and antineurodegenerative potential of Kombucha fermented Camellia sinensis, Coffea arabica and Ganoderma lucidum extracts

Pavlović

¹

,

Stajić

²

,

Gašić

³

et al. 2023

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“…Likewise, both extract from the stem bark for aqueous and acetone was absent for Steroids. Liquid-liquid fraction is a technique for partitioning the range of compounds in a mixture based on polarity [35]. During the fractions of the crude extracts from Psidium guajava leaf and stem bark, choice of solvent was based on polarity.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Potency of Fractions from <em>Psidium guajava</em> Leaves and Bark Crude Extracts against Bacterial Isolates Responsible for Foodborne Infection

Ndako¹,

Oludipe²,

Junaid³

et al. 2023

Preprint

1

0

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Guava (Psidium guajava L.) is a common fruit tree that grows in several tropical and subtropical parts of the world. The aim of this study was to employ the use of liquid-liquid fractionation to investigative the comparative antibacterial potential of crude extracts of Guava leaves and bark against selected food isolates; Escherichia coli, Pseudomonas aeruginosa, Streptococcus pneumonia, Bacillus cereus and Staphylococcus aureus. The phytochemical analysis of the extract showed presence of tannin, phenol, flavonoid and terpenoid in all extract, while steroid and saponin were absent in some. The agar diffusion method was employed for the assessment of the sensitivity of the extracts. The ethyl acetate and aqueous fractions from the stem bark acetone extract generally showed better antimicrobial activity compared with other extracts from leaves. The extract was active both against gram positive bacteria (Bacillus cereus and Streptococcus pneumonia) and gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa, , Bacillus cereus and Staphylococcus aureus) at varying zone of inhibition. The results of the study showed the potential of identifying novel antibacterial agent from P. guajava bark and leaves while optimising the potential application for treatment in traditional medicine.

show abstract

“…Likewise, both extracts from the stem bark for aqueous and acetone was absent for Steroids. Liquid-liquid fraction is a technique for partitioning the range of compounds in a mixture based on polarity [35]. During the fractions of the crude extracts from Psidium guajava leaf and stem bark, choice of solvent was based on polarity.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Potency of Fractions from <em>Psidium guajava</em> Leaves and Bark Crude Extracts against Bacterial Isolates Responsible for Foodborne Infection

Ndako¹,

Oludipe²,

Junaid³

et al. 2023

Preprint

1

0

View full text Add to dashboard Cite

Guava (Psidium guajava L.) is a common fruit tree that grows in several tropical and subtropical parts of the world. The aim of this study was to employ the use of liquid-liquid fractionation to investigative the comparative antibacterial potential of crude extracts of Guava leaves and bark against selected food isolates; Escherichia coli, Pseudomonas aeruginosa, Streptococcus pneumonia, Bacillus cereus and Staphylococcus aureus. The phytochemical analysis of the extract showed presence of tannin, phenol, flavonoid and terpenoid in all extract, while steroid and saponin were absent in some. The agar diffusion method was employed for the assessment of the sensitivity of the extracts. The ethyl acetate and aqueous fractions from the stem bark acetone extract generally showed better antimicrobial activity compared with other extracts from leaves. The extract was active both against gram positive bacteria (Bacillus cereus and Streptococcus pneumonia) and gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa, , Bacillus cereus and Staphylococcus aureus) at varying zone of inhibition. The results of the study showed the potential of identifying novel antibacterial agent from P. guajava bark and leaves while optimising the potential application for treatment in traditional medicine.

show abstract

Extraction of phytochemicals with health benefit from Peperomia pellucida (L.) Kunth through liquid-liquid partitioning

Cited by 22 publications

References 44 publications

The chemical profiling and assessment of antioxidative, antidiabetic and antineurodegenerative potential of Kombucha fermented Camellia sinensis, Coffea arabica and Ganoderma lucidum extracts

The chemical profiling and assessment of antioxidative, antidiabetic and antineurodegenerative potential of Kombucha fermented Camellia sinensis, Coffea arabica and Ganoderma lucidum extracts

Antibacterial Potency of Fractions from <em>Psidium guajava</em> Leaves and Bark Crude Extracts against Bacterial Isolates Responsible for Foodborne Infection

Antibacterial Potency of Fractions from <em>Psidium guajava</em> Leaves and Bark Crude Extracts against Bacterial Isolates Responsible for Foodborne Infection

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