Extract of Nanas Bongsai (Ananas comosus var. microstachys) on The Histology of The Limph and Uterus of White Rat (Rattus norvegicus)

Abstract

Nanas Bongsai (Ananas comosus var. microstachys L.) is an amazing herb which is used in traditional medicine by local people of Muara Lembu district as a potion to reduce pain while menstruation period for a women. The present work was designed to investigate its probable side effects on the histopathologic changes in limph and uterus tissues after treated with A. comosus var. microstachys L extract in female white rats. This is an experimental research consisted of five treatments and three repetitions. Treatment composed of two controls (P 0 and P + ) and given Nanas Bongsai extract with three different dosages. Histology result of lymph show that all treatments given with Nanas Bongsai with three different dosages have different diameter average of white pulp and there is no significant changes with normal control. While observation towards histology structure of endometrium thickness with dosage P 1 , dosage P 2 , dosage P 3 is 206. 333±33.486; 215.667±33.486; 197.667±60.871 respectively. The most thin endometrium layer found in treatment with dosage P 3 compared to control P 0 . From this study showed that there is no toxic effect on uterus and lymph function of of Nanas Bonsai (A. comosus var. microstachys L.) at different doses, so the plant is secure for consumption by the community.

Histopathological Overview of Kidney and Liver Female White Rat Administered (Ananas comosus var. microstachys L.) Extract as Herbal Plant for Dysmenorrhea

“…Staining process including Hematoxylin-Eosin (HE). Observation and documented using light microscopy (Fitmawati et al, 2018).…”

“…Nanas bongsai has been clinically tested to be safe for consumption and not harmful to organs. Preliminary research has proven that there is no toxic effect on uterine and lymphatic function after administration of different doses of nanas bongsai extract to female white rats (Rattus norvegicus) (Fitmawati et al, 2018). However, preaclinical testing is needed for the function of other organs such as liver and kidneys.…”