Extracranial neurogenic tumors of the head and neck

Curioni, Otávio Alberto; Souza, Ricardo Pires de; Mercante, Ana Maria da Cunha; Jesus, Ana Carolina de; Pavelegeni, Alysson; Dedivitis, Rogério Aparecido; Rapoport, Abrão

doi:10.1016/j.bjorl.2015.08.012

Cited by 12 publications

(12 citation statements)

References 22 publications

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“…Extracranial schwannomas have a high predilection for the neck, notably parapharyngeal space [4], as was the case with our institutional data (Table 1). The most common nerves of origin for extracranial head and neck schwannomas is from vagus and sympathetic nerves [5].…”

Section: Discussionsupporting

confidence: 82%

Unusual Sites for Extracranial Head–Neck Schwannomas

Zubair

Kumar

Jat

et al. 2020

Indian J Otolaryngol Head Neck Surg

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Schwannomas are a frequent cause of swellings in the head and neck region. Due to the abundance of peripheral, cranial and autonomic nerves in this region, schwannomas can present in variety of locations, posing a diagnostic and therapeutic challenge to the surgeon. Unusual sites in head and neck region can have varied presentation depending on the site of origin. We identified unusual extracranial locations of head and neck schwannomas, their presenting features and surgical management. Retrospective review of cases of extracranial head and neck schwannomas operated in the Department of Otolaryngology and Head-Neck Surgery, All India Institute of Medical Sciences, New Delhi, a tertiary referral centre between July 2015 and June 2019. A total of 42 cases of extracranial head and neck schwannomas were operated. Among them, 9 cases were found to arise from uncommon sites, such as parotid gland (n = 1), infratemporal fossa (n = 2), external auditory canal (n = 1), subglottis (n = 1), false vocal cord (n = 1), frontal recess (n = 1), maxillary sinus (n = 1) and retromolar trigone (n = 1). All patients underwent excision via relevant approaches. Nerve of origin was identified in 4/9 cases. One case had postoperative neurological deficit. No recurrences were noted in mean follow-up of 19 months. Schwannomas ought to be considered as a differential diagnosis for swellings/ mass in any part of head and neck region. Comprehensive evaluation with appropriate imaging and histology should be done in all cases. Preoperative counselling and consent regarding neurological deficit pertaining to possible nerve of origin is required in each case.Keywords Schwannoma Á Nerve sheath tumour Á Extracranial Á Head and neck Á Nerve of origin MethodsA retrospective case note study was carried out for all patients with a diagnosis of schwannoma seen in the

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Section: Discussionsupporting

confidence: 82%

Unusual Sites for Extracranial Head–Neck Schwannomas

Zubair

Kumar

Jat

et al. 2020

Indian J Otolaryngol Head Neck Surg

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“…Embriyonik nöral krestten gelişen nörojenik tümörler, köken aldıkları hücreye göre 3 grupta sınıflandırılırlar. 1,2 Bunlar; periferik sinir kılıfı, sempatik ganglion hücreleri ve paraganglionik hücrelerden gelişen tümörlerdir. 1,2 Nörojenik kökenli tümörler baş ve boyun bölgesinde nadiren görülürler.…”

Section: Discussionunclassified

“…1 Baş ve boyun bölgesinde görülme sıklığı %25-40 arasında bildirilmektedir. 1,2 Parafaringeal schwannomalar genellikle lokalizasyon ve koken aldıkları sinirlere göre mediyal ve lateral grup şeklinde 2'ye ayrılırlar. Mediyal grubu IX, X, XI ve XII.…”

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Brakial Pleksustan Gelişen Schwannoma

Özer¹,

Vural²,

Canpolat³

2021

KBB ve BBC Dergisi

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Schwannomalar (Neurilemmoma), periferik sinir kılıfı hücresi Schwann hucrelerinden gelişen, coğunlukla iyi huylu, soliter tumorlerdir. 1 Baş ve boyun bölgesinde görülme sıklığı %25-40 arasında bildirilmektedir. 1,2 Parafaringeal schwannomalar genellikle lokalizasyon ve koken aldıkları sinirlere göre mediyal ve lateral grup şeklinde 2'ye ayrılırlar. Mediyal grubu IX, X, XI ve XII. kraniyal sinirlerden kaynaklanan parafaringeal schwannomalar oluştururken, lateral grubu servikal ve brakial pleksustan kaynaklanan servikal sempatik zincir schwannomaları oluşturur. 1 Bunun yanında, Schwann hucrelerinin bulunduğu her yerde bu tumorlere rastlanabilir. Makalemizde, brakial pleksustan köken alan schwannoma olgusu sunulmuş ve literatür gözden geçirilmiştir. OLGU SUNUMU27 yaşında kadın hasta, 2 yıldır boyun sağ tarafındaki ağrısız şişlik şikâyeti ile kliniğimize başvurdu. Fizik muayenede, sağ supraklaviküler bölgede 3x2 cm boyutlarında sert, fikse tümöral kitle tespit edildi. Rutin kulak-burun-boğaz muayenesinde ek patoloji saptanmadı. Sağ kolda hissizlik, güç kaybı, fonksiyon kaybı, kas atrofisi, ödem, şişlik veya ciltte renk değişikliği gibi eşlik eden ek semptom yoktu. Kitlenin supraklaviküler bölge yerleşimli olması nedeniyle kontrastlı boyun bilgisayarlı tomografi (BT), toraks BT ve abdomen ultrasonografi (USG) tetkikleri yapıldı. Toraks BT ve abdomen USG tetkiklerinde patolojik bulgu saptanmadı. Boyun BT

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“…Neurogenic tumors that originate from neural crest derivatives occur in the head and neck in 25–45% of cases [ 1 – 3 ]. Head and neck malignant neurogenic tumors commonly present as nasal obstructions, indolent masses and partly with Horner’s syndrome.…”

Section: Introductionmentioning

confidence: 99%

A population-based analysis of clinical features and lymph node dissection in head and neck malignant neurogenic tumors

et al. 2021

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Background The influence of lymph node dissection (LND) on survival in patients with head and neck neurogenic tumors remains unclear. We aimed to determine the effect of LND on the outcomes of patients with head and neck neurogenic tumors. Methods Data of patients with surgically treated head and neck neurogenic tumors were identified from the Surveillance, Epidemiology, and End Results (SEER) database (1975–2016) to investigate the relationship between LND and clinical outcomes by survival analysis. Subgroup analysis was performed in IVa and IVb group. Results In total, 662 head and neck neurogenic tumor patients (median age: 49.0 [0–91.0] years) met the inclusion criteria, of whom 13.1% were in the IVa group and 86.9% were in the IVb group. The median follow-up time was 76.0 months (range: 6.0–336.0 months), and the 5-year and 10-year overall survival was 82.4% (95% CI, 0.79–0.85) and 69.0% (95% CI, 0.64–0.73). Cox regression analysis revealed older age (P < .001), advanced stage (P = .037), African American race (P = .002), diagnosis before 2004 (P < .001), and chemotherapy administration (P < .001) to be independent negative predictors of overall survival. Kaplan-Meier analysis demonstrated that LND was not a predictor of clinical nodal negativity (cN0) in either IVa or IVb patients. Conclusions In head and neck neurogenic patients, LND may not impact the outcome of cN0 in either IVa or IVb group. These data can be recommended in guiding surgical plan and future studies.

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Extracranial neurogenic tumors of the head and neck

Abstract: Extracranial neurogenic tumors presented with a mean size of 5.5cm, were located laterally in the neck, normally had their origin from cranial nerves, and their resection approach is cervical.

Cited by 12 publications

References 22 publications

Unusual Sites for Extracranial Head–Neck Schwannomas

Unusual Sites for Extracranial Head–Neck Schwannomas

Brakial Pleksustan Gelişen Schwannoma

A population-based analysis of clinical features and lymph node dissection in head and neck malignant neurogenic tumors

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