Extracorporeal photochemotherapy alone or with adjuvant therapy in the treatment of cutaneous T-cell lymphoma: A 9-year retrospective study at a single institution

Bisaccia, Emil; Gonzalez, J.R. Flores; Palangio, Mark; Schwartz, Joseph; Klainer, Albert S.

doi:10.1067/mjd.2000.104852

Cited by 62 publications

(53 citation statements)

References 25 publications

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“…The most frequent tumor of benign dignity is a syringocystadenoma papilliferum (8–19%), the most frequent malignant tumor is basal cell carcinoma [9]. Some authors postulate that trichoblastoma, and not basal cell carcinoma, is the most frequent tumor associated with nevus sebaceus [10]. …”

Section: Discussionmentioning

confidence: 99%

Schimmelpenning-Feuerstein-Mims Syndrome with Hypophosphatemic Rickets

Zutt¹,

Strutz²,

Happle³

et al. 2003

Dermatology

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The Schimmelpenning-Feuerstein-Mims syndrome (SFM syndrome) is a rare and variable multisystem defect consisting of congenital, extensive linear nevus sebaceus and associated abnormalities in different neuroectodermal organ systems. We present the history of a 52-year-old female patient with disproportionate hyposomia and asymmetric constitution. From birth she suffered from a right-sided, extensive nevus sebaceus following Blaschko’s lines extending on the scalp, neck, right arm and trunk. At the age of 5 years, she developed a generalized growth retardation, along with deformations of bones. At the age of 11, hypophosphatemic rickets was diagnosed causing this growth retardation. Moreover, the patient developed a precocious puberty at the age of 9 years. When we saw the patient 40 years after the diagnosis had been made, phosphaturia had returned to normal. Specific therapy of hypophosphatemic rickets is straightforward and efficient in preventing late complications like growth retardation. We suggest to conduct appropriate laboratory tests in early childhood in patients with an extensive systematized sebaceous nevus or with additional signs of growth retardation or skeletal involvement, in order to exclude hypophosphatemic rickets associated with SFM syndrome.

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Section: Discussionmentioning

confidence: 99%

Schimmelpenning-Feuerstein-Mims Syndrome with Hypophosphatemic Rickets

Zutt¹,

Strutz²,

Happle³

et al. 2003

Dermatology

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“…Beste Ansprechraten zeigen CTCL-Patienten mit relativ intaktem Immunsystem und mit einer Krankheitsdauer unter 2 Jahren ohne Befall von Lymphknoten oder inneren Organen. Mehrere Studien konnten verbesserte Ansprechraten durch Kombinationstherapien von ECP mit Ganzkörperradiatio, Bestrahlung mittels schneller Elektronen, PUVA, Rexinoiden, Chemotherapien sowie Interferontherapien zeigen [3].…”

Section: Die Therapeutische Ansprechrate Von Extrakorporaler Photopunclassified

Update zur extrakorporalen Photopherese

Just

Knobler

2015

Hautarzt

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Extracorporeal photopheresis (ECP) is a treatment approach that combines leukapheresis with photochemotherapy and is derived from PUVA; with this procedure, nucleated cells such as lymphocytes and monocytes are extracorporeally irradiated with UVA light after photosensitization. ECP is an effective treatment modality with few side effects that in recent years has been expanded to treat a range of indications. It has been proven effective in the treatment of cutaneous T cell lymphoma and is being increasing used in other lymphocyte-mediated, autoimmune and inflammatory diseases that are associated with proliferation of autoreactive T cells.

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“…137 Studies involving ECP as a monotherapy have shown partial response rates from 20% to 88% and complete response rates of 13% to 33% of patients. [138][139][140][141][142][143][144][145][146][147][148][149][150][151][152] Studies demonstrating that ECP clinically improves and prolongs survival in patients with erythrodermic and advanced-stage CTCL support the use of ECP as first-line for stages III and IV patients. 126,144,153,159 There is controversy regarding the benefit of ECP in SS in prolonging survival.…”

Section: Photopheresis and Combined Immunomodulatory Therapymentioning

confidence: 99%

Choosing a systemic treatment for advanced stage cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome

Duvic

2015

Hematology

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Extracorporeal photochemotherapy alone or with adjuvant therapy in the treatment of cutaneous T-cell lymphoma: A 9-year retrospective study at a single institution

Cited by 62 publications

References 25 publications

Schimmelpenning-Feuerstein-Mims Syndrome with Hypophosphatemic Rickets

Schimmelpenning-Feuerstein-Mims Syndrome with Hypophosphatemic Rickets

Update zur extrakorporalen Photopherese

Choosing a systemic treatment for advanced stage cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome

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