Extracorporeal Life Support Organization Registry Report 2022

Rycus, Peter; Stead, Christine

doi:10.1055/s-0042-1757394

Cited by 16 publications

(7 citation statements)

References 1 publication

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“…The overall survival following ECMO support is 55%-60% according to the ELSO database. 53 Centres achieving 80%-85% survival rate have very strict patient-selection criteria as emphasised by a recent meta-analysis. 54 Its findings are consistent with higher than predicted mortality in burn patients requiring ECMO support although the subgroup of patients with inhalation injury shows lower than predicted mortality rate.…”

Section: Discussionmentioning

confidence: 99%

Extracorporeal Life Support in Adult Burn Care: A Systematic Review

et al. 2023

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We sought to review the role of extracorporeal membrane oxygenation (ECMO) for the management of burn and smoke inhalation injury in the adult patient population. Therefore, we conducted a systematic search of the literature according to specific combination of key words to ascertain the effectiveness of this support strategy. A total of 26 articles were filtered out of 269 and considered suitable for this study. The PICOS approach and PRISMA flow chart were followed for the purposes of our review. Although there is growing evidence supporting the role of ECMO as an option for burn injury in the adult patient population, this strategy should be considered if a likely successful outcome is expected.

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Section: Discussionmentioning

confidence: 99%

Extracorporeal Life Support in Adult Burn Care: A Systematic Review

et al. 2023

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“…Extracorporeal membrane oxygenation (ECMO) is used to treat over 19,000 patients each year for respiratory failure, cardiogenic shock, cardiac arrest, or employed as extracorporeal cardiopulmonary resuscitation (ECPR). 1 Historically, ECMO has been predominately used in neonatal and pediatric populations, though in the past two decades, cases of adult ECMO have been on the rise and now account for the majority of cases. 1,2 The adult use of ECMO recently saw even further expansion with the COVID-19 pandemic.…”

Section: Introductionmentioning

confidence: 99%

“…1 Historically, ECMO has been predominately used in neonatal and pediatric populations, though in the past two decades, cases of adult ECMO have been on the rise and now account for the majority of cases. 1,2 The adult use of ECMO recently saw even further expansion with the COVID-19 pandemic. 3 Issues with thrombosis and bleeding are some of the most common ECMO complications.…”

Section: Introductionmentioning

confidence: 99%

Novel tubing connectors reduce ECMO circuit thrombosis

Bresette,

Shea,

Wagoner

et al. 2024

Int J Artif Organs

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Background: Thrombosis within extracorporeal membrane oxygenation (ECMO) circuits is a common complication that dominates clinical management of patients receiving mechanical circulatory support. Prior studies have identified that over 80% of circuit thrombosis can be attributed to tubing-connector junctions. Methods: A novel connector was designed that reduces local regions of flow stagnation at the tubing-connector junction to eliminate a primary source of ECMO circuit thrombi. To compare clotting between the novel connectors and the traditional connectors, both in vitro loops and an in vivo caprine model of long-term (48 h) ECMO were used to generate tubing-connector junction clots. Results: In vitro, the traditional connectors uniformly (9/9) formed large thrombi, while novel connectors formed a small thrombus in only one of nine ( p < 0.0001). In the long-term goat ECMO circuits, the traditional connectors exhibited more thrombi ( p < 0.04), and these thrombi were more likely to protrude into the lumen of the tubing ( p < 0.001). Conclusion: Both in vitro and in vivo validation experiments successfully recreated circuit thrombosis and demonstrate that the adoption of novel connectors can reduce the burden of circuit thrombosis.

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“…In this context, extracorporeal cardiopulmonary resuscitation (ECPR) has been first introduced as ultima ratio in 1966 [ 1 ]. Almost 6 decades later, more than 15,000 ECPR cases are registered in the Extracorporeal Life Support Organization (ELSO) registry [ 2 , 3 ] with a survival rate of 30%. This review will discuss the background, indications, challenges, and limitations of ECPR.…”

Section: Introductionmentioning

confidence: 99%

Extracorporeal cardiopulmonary resuscitation in 2023

Wengenmayer,

Tigges,

Staudacher

2023

ICMx

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Extracorporeal Life Support Organization Registry Report 2022

Cited by 16 publications

References 1 publication

Extracorporeal Life Support in Adult Burn Care: A Systematic Review

Extracorporeal Life Support in Adult Burn Care: A Systematic Review

Novel tubing connectors reduce ECMO circuit thrombosis

Extracorporeal cardiopulmonary resuscitation in 2023

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