Extracellular Vesicles in Ovarian Cancer: From Chemoresistance Mediators to Therapeutic Vectors
Barathan Muttiah,
Nur Dina Muhammad Fuad,
Faizul Jaafar
et al.
Abstract:Ovarian cancer (OC) remains the deadliest gynecological malignancy, with alarming projections indicating a 42% increase in new cases and a 51% rise in mortality by 2040. This review explores the challenges in OC treatment, focusing on chemoresistance mechanisms and the potential of extracellular vesicles (EVs) as drug delivery agents. Despite advancements in treatment strategies, including cytoreductive surgery, platinum-based chemotherapy, and targeted therapies, the high recurrence rate underscores the need … Show more
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