Extracellular vesicles as next-generation therapeutics and biomarkers in amyloidosis: a new frontier
Thanh Huyen Phan,
Joanne H. Reed
Abstract:Nanoparticles hold a great potential for therapeutic targeting due to their ability to improve the stability of encapsulated cargo and promote the transport of cargo across membranes to reach to the target site. Most commercially available nanomedicines are simple synthetic liposomes, however, there are numerous side effects due to their off-target delivery and rapid clearance from the bloodstream. Recently, attention has moved toward extracellular vesicles (EVs)–lipid bilayer enclosed particles released by ce… Show more
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