Extracellular vesicles as biomarkers for AIDS-associated non-Hodgkin lymphoma risk
Laura E. Martínez,
Larry I. Magpantay,
Yu Guo
et al.
Abstract:IntroductionExtracellular vesicles are membrane-bound structures secreted into the extracellular milieu by cells and can carry bioactive molecules. There is emerging evidence suggesting that EVs play a role in the diagnosis, treatment, and prognosis of certain cancers. In this study, we investigate the association of EVs bearing PD-L1 and molecules important in B-cell activation and differentiation with AIDS-NHL risk.MethodsEVs were isolated from archived serum collected prior to the diagnosis of AIDS-NHL in c… Show more
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