Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19
Thea N. Golden,
Sneha Mani,
Rebecca L. Linn
et al.
Abstract:SARS-CoV-2 infection and the resulting coronavirus disease (COVID-19) complicate pregnancies as the result of placental dysfunction which increases the risk of adverse pregnancy outcomes. While abnormal placental pathology resulting from COVID-19 is common, direct infection of the placenta is rare. This suggests maternal response to infection is responsible for placental dysfunction. We hypothesized that maternal circulating extracellular vesicles (EVs) are altered by COVID-19 during pregnancy and contribute t… Show more
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