Abstract:Advanced age is a major risk factor for age‐related degenerative tendinopathy. During aging, tendon stem/progenitor cell (TSPC) function declines owing to the transition from a normal quiescent state to a senescent state. Extracellular vesicles (EVs) from young stem cells are reported to possess anti‐aging functions. However, it remains unclear whether EVs from young TSPCs (TSPC‐EVs) can rejuvenate senescent TSPCs to delay age‐related degeneration. Here, this study finds that TSPC‐EVs can mitigate the aging ph… Show more
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