Extracellular vesicle analysis in supramolecular 3D hydrogels: a proof-of-concept

Bergamaschi, Greta; Frigerio, Roberto; Musicò, Angelo; Lodigiani, Giulia; Gagni, Paola; Vago, Riccardo; Cretich, Marina; Gori, Alessandro

doi:10.1039/d3sd00313b

Sens. Diagn.

2024

DOI: 10.1039/d3sd00313b

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Extracellular vesicle analysis in supramolecular 3D hydrogels: a proof-of-concept

Greta Bergamaschi,

Roberto Frigerio,

Angelo Musicò

et al.

Abstract: In the present work, we report a proof-of-concept application of a composite Aga-Q3 hydrogel for the gentle confinement and analysis of extracellular vehicles (EVs) on microarray analytical platforms. Thanks to...

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Supramolecular Hydrogels for 3D Biosensors and Bioassays

Gagni,

Lodigiani,

Frigerio

et al. 2024

Chemistry A European J

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Supramolecular hydrogels play a pivotal role in many fields of biomedical research, including emerging applications in designing advanced tools for point‐of‐care testing, clinical diagnostics, and lab‐on‐chip analysis. This review outlines the growing relevance of supramolecular hydrogels in biosensing and bioassay devices, highlighting recent advancements that deliver increased sensitivity, real‐time monitoring, and multiplexing capabilities through the distinctive properties of these nanomaterials. Furthermore, the exploration extends to additional applications, such as using hydrogels as three‐dimensional matrices for cell‐based assays.

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Supramolecular Hydrogels for 3D Biosensors and Bioassays

Gagni,

Lodigiani,

Frigerio

et al. 2024

Chemistry A European J

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Extracellular vesicle analysis in supramolecular 3D hydrogels: a proof-of-concept

Abstract: In the present work, we report a proof-of-concept application of a composite Aga-Q3 hydrogel for the gentle confinement and analysis of extracellular vehicles (EVs) on microarray analytical platforms. Thanks to...

Cited by 1 publication

References 42 publications

Supramolecular Hydrogels for 3D Biosensors and Bioassays

Supramolecular Hydrogels for 3D Biosensors and Bioassays

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