Extracapillary IgA Nephropathy and Pulmonary Tuberculosis

Fofi, Claudia; Cherubini, Chiara; Barbera, G; Nicoletti, Maria Concetta Domenica; Giulio, Salvatore Di

doi:10.1097/01.cpm.0000181642.91898.6e

Cited by 7 publications

(10 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Conversely, the previous episode of AKI and remaining chronic kidney disease and hematoproteinuria suggested a previous IgAN which was triggered or acquired an aggressive behaviour in the presence of tuberculosis. An additional case describing C-IgAN associated with tuberculosis was found in the literature 14 .…”

Section: Discussionmentioning

confidence: 98%

“…Some cases of IgAN have been reported in the setting of tuberculosis which may be initiated by the humoral immune response against MTB and the production of IgA immune complexes 12 . Rapidly progressive glomerulonephritis caused by MTB is extremely rare and most cases represent acute postinfectious glomerulonephritis (APIGN) 13,14 . IgA-dominant APIGN is most common in old diabetic patients with staphylococcal infections.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Crescentic IgA nephropathy associated with pleural tuberculosis

Marques¹,

Pereira²,

Marques³

2019

pjnh

View full text Add to dashboard Cite

Crescentic IgA nephropathy represents an aggressive glomerular injury which can cause renal failure unless diagnosed and treated rapidly. There is currently no consensus on the most effective treatment strategy, although immunosuppressive drugs are usually used. Tuberculosis is rarely associated with glomerulonephritis and raises difficult questions about the safety and usefulness of immunosuppressive agents. We report a rare case of rapidly progressive renal failure associated with pleural tuberculosis in a 68-year-old man. The identification of crescents and fibrinoid necrosis in 12 out of 21 glomeruli and IgA deposits in the renal biopsy suggested the diagnosis of crescentic IgA nephropathy. Corticosteroids in combination with antituberculosis drugs were started with significant improvement in his general condition and cure of his pleural tuberculosis but without recovery of kidney function.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Crescentic IgA nephropathy associated with pleural tuberculosis

Marques¹,

Pereira²,

Marques³

2019

pjnh

View full text Add to dashboard Cite

show abstract

“…Anekdotische Berichte weisen darüber hinaus auf einen möglichen Zusammenhang mit mykobakteriellen Infekten hin [5,6,10,11,12,15,16,17,20].…”

Section: Partielle Klinische Remission Einer Chronischen Iga-nephropaunclassified

“…Ein kausaler Zusammenhang zwischen Infektionen durch Mycobacterium tuberculosis und der mesangialen [5,6,11,15,16,17] oder extrakapillär proliferierenden Verlaufsform [10,20,21] Partial clinical remission of chronic IgA nephropathy with therapy of tuberculosis 5 History and clinical findings: A 36-year-old patient suffered from repeated exsudative pleural effusions and renal insufficiency (serum creatinine 1.9 mg/dl) combined with glomerular erythrocyturia, proteinuria and renal hypertension.…”

mentioning

confidence: 99%

Partielle klinische Remission einer chronischen IgA-Nephropathie unter antituberkulotischer Therapie

Ortmann

Schiffl

2010

Dtsch med Wochenschr

View full text Add to dashboard Cite

show abstract

“…Out of the 17 cases of glomerulonephritis associated with Tuberculosis reported in literature [7][8][9]; six were associated with IgA nephropathy [10,11], four were crescents [12], two were mesangial proliferative [13][14][15], two were membranous nephropathy [16]; and one each of mesangiocapillary and collapsing glomerulopathy [16].…”

Section: Introductionmentioning

confidence: 99%

Crescentic Glomerulonephritis with Tubercular Lymphadenitis

Katyal¹,

Tewari²

2020

J Clin Nephrol Ren Care

View full text Add to dashboard Cite

A 65-year-old lady presented with history of fever of three weeks duration and gradually developed puffiness of face and limbs, since a week. She had reduced appetite and decreasing urine output since one week as well. Fever was moderate grade; not associated with any chills, rigors or showed any diurnal variation. There was no history of cough, breathlessness, haemoptysis, skin rash, joint pains, mouth ulcers, pain abdomen, haemeturia, ocular complaints. On clinical evaluation, she had oedema, temperature of 101 deg F, BP was 160/90 mm of Hg. Right arm was supine. She had a two cm firm and on tender lymph node palpable in the right axillary region of the medial group. Systemic examination was unremarkable. Initial investigations revealed Hb 10.4 gm/dl, TLC: 12,200/cumm, DLC: (Neutrophils 79%, Lymphocytes 18%, Monocytes 2% and Eosinophils 1%), Platelets 4, 00,000 per cubic mm, ESR: 68 mm, CRP: 9.0 mg/L, BUN 30 mg/dl, serum creatinine of 2.4 mg/dl. Urine showed numerous dysmorphic RBCs per high power field, and urine dipstick showed 2+ proteins. Twenty four hour urinary protein excretion was 1.3 gm per day. She had rapidly worsening renal function with reduced urine output and her serum creatinine increased to 5.8 mg/dl over the next one week. Ultrasound of the abdomen revealed multiple retroperitoneal Lymph Nodes along with mesenteric lymph nodes forming a lymph node mass. The size of the lymph node mass was 2.2 × 1.7 cm. Her sputum for both acid fast bacilli (AFB) and Gene expert for Mycobacterium tuberculosis was negative. A non-contrast CT scan of the chest and abdomen revealed multiple lymph nodes; Preaotric, Paraortic, Precaval and Peripancreatic region, along with mesenteric lymph nodes

show abstract

Extracapillary IgA Nephropathy and Pulmonary Tuberculosis

Cited by 7 publications

References 19 publications

Crescentic IgA nephropathy associated with pleural tuberculosis

Crescentic IgA nephropathy associated with pleural tuberculosis

Partielle klinische Remission einer chronischen IgA-Nephropathie unter antituberkulotischer Therapie

Crescentic Glomerulonephritis with Tubercular Lymphadenitis

Contact Info

Product

Resources

About