Extra-Axial Cerebellopontine Angle Medulloblastoma in an Infant

Abstract

Medulloblastoma is a common tumor of the posterior fossa, representing 20-25% of all pediatric neoplasms. It commonly occurs in the midline (cerebellar vermis) and rarely at the cerebellopontine angle. Most of them are intra-axial, and an extra-axial location of this tumor is very rare. Extra-axial cerebellopontine angle medulloblastoma is extremely uncommon and has never been reported in an infant. We report an extra-axial cerebellopontine anglemedulloblastoma in a 1-year-old child.

Extra-axial Cerebellopontine Angle Adult Medulloblastoma: An Unusual Presentation at an Unusual Site

“…In 2007, WHO designated it as a distinct embryonal tumor, distinguishing it from other primitive neuroectodermal tumors (PNETs). 2 Medulloblastoma is predominantly a pediatric tumor accounting for one-fourth of all pediatric intracranial tumors. The most common site is the cerebellar vermis, from where it penetrates the fourth ventricle, resulting in abnormalities in the flow of cerebrospinal fluid (CSF).…”

“…1 In adults, the tumor is uncommon, accounting for approximately 1% of adult primary brain tumors and 6% of posterior fossa tumors, 80% of which occur before the end of the fourth decade. 1,2 The incidence of adult Medulloblastoma is approximately 0.5 per million per year and decreases with increasing age. The published studies on adult medulloblastoma are usually retrospective, owing to its rarity in adult populations, and are mostly midline (cerebellar vermis).…”

“…The published studies on adult medulloblastoma are usually retrospective, owing to its rarity in adult populations, and are mostly midline (cerebellar vermis). 1,2 We report an extremely rare occurrence of adult cerebellopontine angle (CPA) medulloblastoma. This case underlines the existence of the extremely rare intra-axial adult tumor in this unusual location, mimicking as a purely extra-axial lesion, thereby confounding its diagnosis.…”

“…There are only 40 reported cases of CPA medulloblastoma in the literature, with most being intra-axial. [2][3][4][5] Extra-axial CPA medulloblastoma is extremely rare and only 10 adult cases have been reported in world literature. 6…”

Extraaxial cerebellopontine angle medulloblastoma with multiple intracranial metastases in adult: A rare case report with a review of literature

“…[ 1 ] In adults, the tumor is uncommon, accounting for approximately 1% of adult primary brain tumors and 6% of posterior fossa tumors, 80% of which occur before the end of the fourth decade. [ 1 2 ] Cerebellopontine angle (CPA) MBs are very rare, and mostly, they are intra-axial. Extra-axial CPA MB is extremely rare and only 11 adult cases have been reported in world literature.…”