Extra-Axial Cerebello-Pontine Angle Medulloblastoma

Faleiro, Rodrigo Moreira; Moraes, Vítor Vieira de Souza; Alves, Maria Teresa de Seixas; Pedrosa, Moisés Salgado; Garcia, Luiz Alberto Otoni; Fontoura, Renato Rinco; Lobato, Vanessa Alves; Rodrigues, Diego Silveira; Martins, Laura Vilaça Carvalho Viégas

doi:10.1055/s-0036-1584552

Cited by 1 publication

(2 citation statements)

References 11 publications

(20 reference statements)

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“…The foramen magnum location has not been reported previously as a separate origin of extra-axial medulloblastomas. Nevertheless, many of the previously reviewed locations exhibit medulloblastoma extension through the foramen magnum without a clear sign of origin [ 28 ]. This is particularly true for lesions that originate from the CPA with caudal descent [ 28 , 29 ].…”

Section: Discussion Of Clinical Review Resultsmentioning

confidence: 99%

“…Nevertheless, many of the previously reviewed locations exhibit medulloblastoma extension through the foramen magnum without a clear sign of origin [ 28 ]. This is particularly true for lesions that originate from the CPA with caudal descent [ 28 , 29 ]. These lesions might present as a physical pit in the brain (i.e., a morphological change), and the diagnostic neuroradiologist should be attentive for such an exceedingly uncommon occurrence [ 30 ].…”

Section: Discussion Of Clinical Review Resultsmentioning

confidence: 99%

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Posterior fossa extra-axial variations of medulloblastoma: a pictorial review as a primer for radiologists

et al. 2021

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Manifestations of an atypical variant of medulloblastoma of the posterior fossa in extra-axial locations have been reported, and key questions concerning its interpretation have been raised previously. This review illustrated the clinico-radiological and histopathological features of the posterior fossa extra-axial medulloblastoma and described possible management strategies. We thoroughly reviewed all atypical anatomical locations of medulloblastoma reported within the posterior fossa and extra-axial spaces. The main characteristics of diagnostic imaging and histopathological results, primarily the distinctive radiopathological characteristics, were summarized to distinguish between intra- and extra-axial medulloblastoma, or pathologies mimicking this tumor. Most cases of posterior fossa extra-axial medulloblastoma have been reported in the cerebellopontine angle, followed by the tentorial and lateral cerebellar locations. The dural tail sign, which is commonly observed in meningioma, is rarely seen in intra- or extra-axial medulloblastoma and might be associated with other benign or malignant lesions. In addition to magnetic resonance imaging, the proposed new imaging techniques, including advances in modern neuroimaging modalities, were discussed, as potentially efficient modalities for characterizing extra-axial medulloblastoma. Radionuclide imaging and magnetic resonance perfusion imaging are practical alternatives to limit the number of differential diagnoses. We believe that medulloblastoma cases are likely under-reported because of publication bias and frequent tumors in unusual locations. Addressing these issues would help establish a more accurate understanding of this entity.

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Section: Discussion Of Clinical Review Resultsmentioning

confidence: 99%