Extra-articular manifestations of rheumatoid arthritis.

Abstract

A full report is being prepared. While the association of bulk sales of these aerosols to occasional asthma deaths appears established, the exact nature of causation is not known. There is a need for more basic research on the effect of isoprenaline in man. It may well be that certain asthmatics develop an idiosyncrasy to it rather than a dosedependent effect on a hypoxic myoiardium in severe airways obstruction. This thought has occurred because of the beneficial use of intravenous isoprenaline in some low output states not always with a healthy myocardium or fully oxygenated arterial blood, and because of the apparently innocuous or moderate airways-obstruction present in many asthmatics shortly before an unexpected death.-I am, etc., W. D. LINEHAN.

Rheumatoid arthritis with pachymeningitis – a case presentation and review of the literature

“…Cervical myelopathy due to atlanto-axial subluxation is the most well-known CNS manifestation in the course of RA, others include spinal cord compression, subdural hematoma [11], cerebral vasculitis, rheumatoid nodule formation and pachymeningitis [12]. The first suggestion of pachymeningitis due to RA was by Wells [13] in 1969, since then there have been a number of reviews and reports which showed CNS involvement in RA patients.…”