2020
DOI: 10.1590/1678-4685-gmb-2019-0064
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Extinction and emergence of genomic haplotypes during the evolution of Avian coronavirus in chicken embryos

Abstract: Avian coronavirus (AvCoV) is ubiquitously present on poultry as a multitude of virus lineages. Studies on AvCoV phenotypic traits are dependent on the isolation of field strains in chicken embryonated eggs, but the mutant spectrum on each isolate is not considered. This manuscript reports the previously unknown HTS (high throughput sequencing)-based complete genome haplotyping of AvCoV isolates after passages of two field strains in chicken embryonated eggs. For the first and third passages of strain 23/2013, … Show more

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