In response to the build-up of systemic risks and widespread fi nancial vulnerabilities, mainstream policymakers in many countries have adopted macroprudential regulations to mitigate systemic risks in the fi nancial sector as a whole. Islamic fi nance, on the other hand, has its own unique features promising stable fi nancial markets. The experience, however, has shown divergence between the ideal and practiced version of Islamic fi nance, where the majority of Islamic fi nancial contracts are highly similar to those of the conventional fi nancial system. In other words, the proportion of preferred contracts of Islamic fi nance, the PLS modes of fi nance, is small. It has been argued that this exposes the Islamic fi nancial system to systemic risks like the conventional system. Therefore, in the long-run, Islamic fi nancial authority should make effort to realize a genuine version of Islamic fi nance by promoting PLS and equity-based fi nance since it is inherently a self-stabilizing instrument of Islamic fi nance, which eliminates the sources of systemic risks in the fi nancial sector. In the short-run, nevertheless, the Islamic fi nancial system should be subjected to macroprudential regulations, but those instruments and tools that are primarily permissible in sharia, and then compatible with countries' circumstances, should be adopted. In the case of Iran, the analysis shows an urgent need for macroprudential regulations in Iranian banking system.