Over 40 years ago, I became interested in cardiac resuscitation when I watched a patient die of bradycardia and repeated asystolic syncope within 3 weeks of her first Stokes-Adams attack. Some way to stimulate effective cardiac beats was needed that would be quick and easy to apply with the brief time available, and also safe. Cardiac stimulation with an esophageal electrode behind the heart and a second one over the precordium came first to mind in those early days of esophageal electrocardiography. Indeed, this almost noninvasive approach was soon found to be successful in stimulating atrial or ventricular beats in anesthetized dogs when attached to an external pulse generator. The esophageal electrode was discarded, however, when totally noninvasive pacing was achieved more simply with both electrodes placed externally over the precordium.In 1952, noninvasive temporary ventricular pacing was first used clinically to resuscitate two patients repeatedly from recurring asystole.' Noninvasive pacing became established thereafter as an effective means of resuscitation from bradycardia and asystole in many clinical circumstances, or more broadly, whenever a ventricular rhythm was needed at any desired rate or duration.' For example, we soon observed that recurring ventricular tachycardias and fibrillation, including torsade de pointes, were often suppressed by acceleration of the ventricular rate above a threshold critical level for these arrhythmia^.^The need for long-term pacing with an implantable pacemaker became obvious with the first clinical trials of temporary pacing, but it was not until 1958 that this goal was r e a l i~e d .~Many new procedures were developed in the Address for reprints: Paul M. Zoll, M.D., 319 Longwood Ave.,