External auditory canal paraganglioma: an atypical presentation

Grover, Nancy; Amen, Furrat; Gallimore, A. P.; Brookes, G. B.

doi:10.1017/s0022215112002162

Cited by 6 publications

(4 citation statements)

References 7 publications

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“…In most cases, the patients presented with a hearing disturbance because the involved EAC side was filled with the mass. 1,2,7,8) However, in our case, a soft tumor was present in the upper portion of the anterior wall and there was no hearing disturbance. Age, sex, and symptoms are similar for patients with a paraganglioma, which usually occurs in the middle ear.…”

Section: A B Cmentioning

confidence: 49%

“…Although CT and magnetic resonance imaging (MRI) are useful to diagnose paraganglioma of the middle ear, 11) they are not essential for such a diagnosis. 1,2,7) The diagnosis of a paraganglioma requires a histopath-ological examination and immunohistochemistry; Zellballen pattern is observed histopathologically, and immunohistochemical analysis is positive for neuron specific enolase, chromogranin, and s-100 (sustentacular cells). 1,2,7,8) Surgical removal is the first-line treatment for paraganglioma in the head and neck, 14) but conventional radiation therapy can be used if surgery is not possible.…”

Section: A B Cmentioning

confidence: 99%

“…1,2,7) The diagnosis of a paraganglioma requires a histopath-ological examination and immunohistochemistry; Zellballen pattern is observed histopathologically, and immunohistochemical analysis is positive for neuron specific enolase, chromogranin, and s-100 (sustentacular cells). 1,2,7,8) Surgical removal is the first-line treatment for paraganglioma in the head and neck, 14) but conventional radiation therapy can be used if surgery is not possible. 9) A paraganglioma that is confined to the EAC is rare, thus its recurrence should be evaluated through follow-up observation.…”

Section: A B Cmentioning

confidence: 99%

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Paraganglioma of the External Auditory Canal : A Case Report

Seo¹,

Choi²,

Kong³

et al. 2017

J Clin Otolaryngol Head Neck Surg

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Paragangliomas are benign tumors originating from paraganglia and characterized by a collection of small neuroendocrine organs. In the ear, paragangliomas are commonly found in the middle ear or jugular bulb. Paragangliomas of the external auditory canal (EAC) are extremely rare. Here, we present our experience with a 25-yearold woman who was admitted to our otology department for intermittent scanty left otorrhea. A physical examination revealed a 3×4 mm-sized pedunculated mass on upper portion of the anterior wall of the left EAC. Computed tomography revealed a non-specific, soft tissue mass in the left EAC without erosion of the underlying bony canal. An excisional biopsy was performed. Histopathological features favored a diagnosis of paraganglioma. At a 9 month post-operative follow-up, the patient had a patent external auditory canal without recurrence. Paragangliomas tend to be locally destructive, and can lead to disability in the form of hearing loss especially in EAC. Although paraganglioma is a very rare disease, our results indicate that it should be included in the differential diagnosis of an EAC mass.

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Section: A B Cmentioning

confidence: 49%

Section: A B Cmentioning

confidence: 99%

Section: A B Cmentioning

confidence: 99%

See 1 more Smart Citation

Paraganglioma of the External Auditory Canal : A Case Report

Seo¹,

Choi²,

Kong³

et al. 2017

J Clin Otolaryngol Head Neck Surg

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“…Benign and malignant neoplasms that arise from ceruminous glands have overlapping clinical features and morphologic characteristics. Therefore, other tumors of epidermal, EAC, middle ear and mastoid origin such as hidradenoma [21,22], cylindroma [19,23], cholesteatoma, choristoma, exostosis, osteoma, eosinophilic granuloma, paraganglioma [59,60], branchial cleft cysts, basal cell carcinoma [61,62], squamous cell carcinoma [63,64], melanoma [65,66], neuroendocrine adenoma of the middle ear [67][68][69], meningioma [70,71], and extension of benign or malignant salivary gland tumors from parotid gland [31] constitute the major differential diagnoses [28]. Thorough histologic evaluation and imaging studies are essential for accurate diagnosis.…”

Section: Differential Diagnosesmentioning

confidence: 99%

Ceruminous Neoplasms of the Ear

Nagarajan

2018

Head and Neck Pathol

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Ceruminous glands are modified apocrine glands located in the external auditory canal (EAC). Neoplastic lesions arising from these glands are rare in humans and constitute a major differential diagnosis for glandular neoplasms of the EAC. Due to anatomic restrictions, benign and malignant neoplasms present with similar symptoms and to some extent even comparable radiologic features, particularly when the tumors are localized. Biopsies are frequently limited by small size, fragmentation and improper anatomic and architectural orientation, thereby hampering our ability to appreciate the relationship of peripheral edges of the tumor to the surrounding tissue. Benign and malignant tumors may also have overlapping histomorphologic features, which further magnifies the challenges in accurate diagnosis and management strategies. This article summarizes the salient clinical, radiologic and histologic features of common ceruminous gland tumors, in addition to discussing features that can aid in differentiating ceruminous tumors from other EAC tumors and to distinguish benign from malignant entities.

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