Extended versus limited pelvic lymph node dissection during bilateral nerve-sparing radical prostatectomy and its effect on continence and erectile function recovery: long-term results and trifecta rates of a comparative analysis

Hatzichristodoulou, Georgios; Wagenpfeil, Stefan; Wagenpfeil, Gudrun; Maurer, Tobias; Horn, Thomas; Herkommer, Kathleen; Hegemann, Marie; Gschwend, Jürgen E.; Kübler, Hubert

doi:10.1007/s00345-015-1699-9

Cited by 22 publications

(19 citation statements)

References 28 publications

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“…Indeed, in the series presented here, patients with bilateral NS and the best urinary continence results had the highest number of lymph nodes removed (Table ). This is consistent with Hatzichristodoulou et al , who showed that urinary continence after RP was not inferior in patients who underwent an extended PLND, in a template similar to the one used by us, when compared to patients with a limited (obturator fossa only) PLND.…”

Section: Discussionsupporting

confidence: 92%

Nerve‐sparing radical cystectomy has a beneficial impact on urinary continence after orthotopic bladder substitution, which becomes even more apparent over time

et al. 2018

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Section: Discussionsupporting

confidence: 92%

Nerve‐sparing radical cystectomy has a beneficial impact on urinary continence after orthotopic bladder substitution, which becomes even more apparent over time

et al. 2018

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“…Two additional studies showed a statistically significant benefit of ePLND over limited/standard PLND but only in specific sub-groups of patients: intermediate-risk patients (96% vs. 90%; p=0.017) [38], and pN1 patients with <15% of retrieved nodes affected (43% vs. 10%; p=0.01) [43]. However, counter-intuitive findings were observed in a retrospective study where ePLND was associated with higher risk of 7-year BCR compared with lPLND in pT2 patients only (5% vs. 0%; p=0.01) [37]. This result may reflect the selection bias of the study, as surgeons tended to perform more extensive nodal dissection in higher risk patients.…”

Section: Biochemical Recurrencementioning

confidence: 91%

The Benefits and Harms of Different Extents of Lymph Node Dissection During Radical Prostatectomy for Prostate Cancer: A Systematic Review

et al. 2017

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The use of online course material is the approach adopted by most universities to support students' revision, and teachers usually have the responsibility for designing or uploading online materials on their own course websites. However, some teachers might lack programming skills or motivation, and most current online materials are just uploaded in a static format (such as PDF) which is not suitable for all students. Moreover, during revision periods students may be faced with a lot of unorganised materials to be revised in a short period of time, and this can lead to an ineffective revision process. In order to address these issues, this paper proposes a software framework that aims to maximise the benefit of current online materials when used to support student revision. This framework is called SRECMATs (Self-Revision E-Course MATerials) and has been deployed as a tool that allows teachers to automatically create an intelligent tutoring system to manage online materials without any programming knowledge, and to support students to navigate easily through these online materials during their revision. This paper evaluates the proposed framework in order to understand students' perceptions with regard to the use of the system prototype, and the results indicate which features are suitable for providing online revision materials as well as confirming the benefit of the revision framework.

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“…Of note, pelvic lymph node dissection was not associated with an increased risk of postoperative ED. 27 Only patient age at surgery, preoperative erectile function, and pathologic tumor stage predicted erectile function recovery.…”

Section: Pelvic Surgerymentioning

confidence: 99%

Understanding and Managing Erectile Dysfunction in Patients Treated for Cancer

Voznesensky

Annam

Kreder

2016

JOP

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Cancer can cause sexual adverse effects by direct and indirect pathways. It can involve sexual organs, indirectly affect body image, or cause fatigue or depression with subsequent effects on libido. Erectile dysfunction (ED), the inability to obtain or maintain an erection firm enough for sexual intercourse, can also result from adverse effects of cancer treatment, such as fatigue, pain, or anxiety about therapy. In addition, depressed feelings about having cancer can affect sexuality, causing a range of signs and symptoms that can lead to ED. Chemotherapy, hormone therapy, surgery, and radiation can all cause sexual adverse effects. Additional factors that play a role include patient age and degree of ED before starting cancer treatment. In this article, we discuss how chemotherapy, hormone therapy, surgery, and radiation affect erectile function as well as possible treatment options for ED.

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Extended versus limited pelvic lymph node dissection during bilateral nerve-sparing radical prostatectomy and its effect on continence and erectile function recovery: long-term results and trifecta rates of a comparative analysis

Abstract: ePLND is not associated with increased risk of postoperative incontinence or erectile dysfunction. Only patient age at surgery, preoperative EF and pathological tumor stage represent predictors of EF recovery.

Cited by 22 publications

References 28 publications

Nerve‐sparing radical cystectomy has a beneficial impact on urinary continence after orthotopic bladder substitution, which becomes even more apparent over time

Nerve‐sparing radical cystectomy has a beneficial impact on urinary continence after orthotopic bladder substitution, which becomes even more apparent over time

The Benefits and Harms of Different Extents of Lymph Node Dissection During Radical Prostatectomy for Prostate Cancer: A Systematic Review

Understanding and Managing Erectile Dysfunction in Patients Treated for Cancer

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