Extended Tables of the Wilcoxon Matched Pair Signed Rank Statistic

McCornack, Robert L.

doi:10.1080/01621459.1965.10480835

Cited by 75 publications

(12 citation statements)

References 7 publications

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“…The Wilcoxon matched-pairs signed-rank test (compare McCornack, 1965) was used for comparing the LA values of VEGF vs. control (n = m = 6; see also Fig. 7), where a significance of 0.05 was obtained (two-sided).…”

Section: Other Statistical Testsmentioning

confidence: 99%

Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application

Kurz

Ambrosy

Wilting

et al. 1995

Developmental Dynamics

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Section: Other Statistical Testsmentioning

confidence: 99%

Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application

Kurz

Ambrosy

Wilting

et al. 1995

Developmental Dynamics

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“…Data are expressed as means & SEM. Statistical analysis of data was performed using the Mann-Whitney two sample rank test [32] and the Wilcoxon matched-pair signed rank test [33]. Correlations between the antiport activity and other parameters were calculated using the formula for the Pearson's correlation coefficient.…”

Section: Determination Of the Erythrocyte Membrane Transport Systemsmentioning

confidence: 99%

The lymphocyte Na⁺/H⁺ antiport: activation in primary hypertension and during chronic NaCl‐loading

Göbel

Hoffmann

Ruppert

et al. 1994

Eur J Clin Investigation

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Increased activity of the Na+/H+ antiport may be a major abnormality in essential hypertension. The activity of this transport system was investigated in lymphocytes from 13 patients with untreated essential hypertension (Ht) and 13 normotensive control subjects (Nt) on an ad libitum (130-170 mmol d-1) NaCl intake. Furthermore, the effects of different states of NaCl balance on lymphocyte Na+/H+ antiport were evaluated in two groups of Nt volunteers receiving 20 vs. 300 mmol d-1 (n = 8) and 85 vs. 200 mmol d-1 (n = 14) of NaCl for 1 week each and in seven Ht patients (20 vs. 300 mmol NaCl d-1 for 1 week each). Additionally, during the 20 and 300 mmol/d NaCl intake red blood cell membrane transport was studied in eight subjects. For the determination of lymphocyte antiport activity, cells were loaded with the cytosolic pH (pHi) indicator bis-carboxyethyl carboxyfluorescein (BCECF-AM) and acidified by addition of different amounts of Na(+)-propionate (5-40 mM). Initial pHi-recovery was taken as the activity of the antiport system and plotted against pHi-values after acidification. Non-linear regression analysis yielded higher 'apparent' maximal transport rates in Ht than Nt (Nt: 2.00 +/- 0.22; Ht: (3.81 +/- 0.59) x 10(-3) s-1; P < 0.025). In contrast, baseline pHi-values and pHi-values at half-maximal activity (pK) were identical in Nt and Ht. In normotensive control subjects on an NaCl intake of 20, 85, 200 and 300 mmol d-1 for 7 d, 'apparent' maximal transport rates averaged 2.75 +/- 0.20, 2.89 +/- 0.17, 2.81 +/- 0.18 and (3.62 +/- 0.25) x 10(-3) s-1, respectively. Thus, antiport activity was significantly (P < 0.05) stimulated on the 300 mmol d-1 intake as compared to the three other NaCl intakes. The extreme intakes of NaCl (20 vs. 300 mmol d-1) in normotensive volunteers did not affect the erythrocyte Na+/K+ pump, Na+/K+ cotransport and Na+/Li+ countertransport. Our study supports the concept that a group of patients with primary hypertension exhibit an activated Na+/H+ antiport. Furthermore, our data demonstrate that a chronic high intake of NaCl is associated with an increase in lymphocyte antiport activity towards the high values observed in primary hypertension.

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“…SEM. Statistical analysis of data was performed using the Mann-Whitney two sample rank test [IS] and the Wilcoxon matched pairs signed rank test [19].…”

Section: Methodsmentioning

confidence: 99%

Sodium balance as a determinant of prostacyclin production by isolated rat aorta

Düsing

Landsberg

Pietsch

et al. 1987

Eur J Clin Investigation

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The present study investigates whether the synthesis of prostacyclin (PGI2) in isolated rat aorta is dependent on the state of sodium balance of the animals. Three groups of ten rats each were included into the study. Two of them were fed a diet low in NaCl for 10 days with group I receiving 0.9% saline and group II distilled water as drinking fluid. Group III received a regular rat chow containing approximately 0.8 mmol day-1 of sodium, also for 10 days. At the end of the dietary protocol, systolic arterial blood pressure was significantly higher in group I (109.9 +/- 2.4 mmHg) as compared to group II (101.0 +/- 2.4 mm Hg; P less than 0.05) and group III animals (102.2 +/- 1.6 mm Hg; P less than 0.05). Generation of PGI2-like activity was determined in portions of the animals' isolated aorta using a platelet aggregation bioassay following incubation in 0.05 M Tris buffer (pH 9.3) for 12, 15, and 30 min, respectively. During these incubation times, generation of PGI2-like activity averaged 48.6 +/- 3.5, 57.8 +/- 4.3 and 68.3 +/- 3.2 pmol mg-1 in group III animals, which had received the regular rat chow, with similar values in the low salt group II (50.2 +/- 2.5, 57.7 +/- 2.7 and 72.9 +/- 3.7 pmol mg-1). Aortic generation of PGI2-like material was significantly suppressed in the high salt group I (37.5 +/- 2.8, 46.2 +/- 3.2 and 61.3 +/- 4.0 pmol mg-1; P less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

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Extended Tables of the Wilcoxon Matched Pair Signed Rank Statistic

Cited by 75 publications

References 7 publications

Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application

Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application

The lymphocyte Na⁺/H⁺ antiport: activation in primary hypertension and during chronic NaCl‐loading

Sodium balance as a determinant of prostacyclin production by isolated rat aorta

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Extended Tables of the Wilcoxon Matched Pair Signed Rank Statistic

Cited by 75 publications

References 7 publications

Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application

Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application

The lymphocyte Na+/H+ antiport: activation in primary hypertension and during chronic NaCl‐loading

Sodium balance as a determinant of prostacyclin production by isolated rat aorta

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The lymphocyte Na⁺/H⁺ antiport: activation in primary hypertension and during chronic NaCl‐loading