Extended survival in a case of metastatic choroidal melanoma with immunotherapy
Ibadulla Mirzayev,
Ahmet Kaan Gündüz,
Leyla Mirzayeva
et al.
Abstract:Uveal melanoma is the most common intraocular malignancy in adults. Despite advances in local treatments, approximately 50% of all cases eventually die from metastatic disease. In cases with metastasis, 2- and 5-year survival rates are approximately 10% and <1%, respectively. Advances in molecular biology have led to the identification of a number of promising drugs including immune checkpoint inhibitors (ICIs). Ipilimumab and nivolumab are ICIs targeting the cytotoxic T-lymphocyte-associated antigen-4 and … Show more
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