Extended spectrum beta-lactamase producing<i>Klebsiella pneumoniae</i>-related keratitis

Eğrilmez, Sait; Palamar, Melis; Sıpahi, Oğuz Reşat; Yağcı, Ayşe

doi:10.1179/1973947812y.0000000053

Cited by 11 publications

(7 citation statements)

References 7 publications

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“…reported a similar case of keratitis after DALK with multidrug resistant K. pneumonia , which completely resolved with sensitive antibiotic, imipenem 5 mg/ml[4] whereas our patient did not. [4] In reDALK, we had left some residual infiltrates, as we had not known about the multidrug resistant organism and because, the DM was clear, we hesitated to do PK.…”

Section: Discussionmentioning

confidence: 59%

“…in which the donor was under long-term intensive care. [4] In our case, the recipient was healthy and so was the donor, who died at the age of 36 years due to fall from height; death was declared on reaching the emergency of the donor hospital. Nevertheless we cannot deny acquisition of the organism from this hospital because in a recent study, Tada et al .…”

Section: Discussionmentioning

confidence: 82%

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A case of acute postoperative keratitis after deep anterior lamellar keratoplasty by multidrug resistant Klebsiella

Bajracharya¹,

Sharma²,

Gurung³

2015

Indian J Ophthalmol

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A healthy lady of 42 years underwent deep anterior lamellar keratoplasty for granular dystrophy. The very next day, it was complicated by development of infectious keratitis. The organism was identified as multidrug resistant Klebsiella pneumoniae. Donor corneal button may be implicated in the transmission of infection in an otherwise uneventful surgery and follow-up. Nosocomial infections are usually severe, rapidly progressive and difficult to treat. Finally, the lady had to undergo therapeutic penetrating keratoplasty for complete resolution of infection.

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Section: Discussionmentioning

confidence: 59%

Section: Discussionmentioning

confidence: 82%

A case of acute postoperative keratitis after deep anterior lamellar keratoplasty by multidrug resistant Klebsiella

Bajracharya¹,

Sharma²,

Gurung³

2015

Indian J Ophthalmol

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“…Klebsiella pneumonia keratitis was reported to be treated with various topical antibiotic ophthalmic suspensions [ 1 , 3 , 6 , 9 ]. In our case, antibiotic susceptibility profile of the isolates came positive for cefoxitin and ciprofloxacin.…”

Section: Discussionmentioning

confidence: 99%

“…Multidrug resistant (MDR) Klebsiella pneumonia is an opportunistic pathogen with a rising mortality rate, occasioned a wide range of community-acquired and nosocomial infections [ 5 ]. Although there are very few reports associated with Klebsiella induced keratitis following deep anterior lamellar keratoplasty (DALK) [ 6 – 8 ], contact lens-related keratitis [ 9 ], and post-corneal repair keratitis [ 10 ], no Klebsiella keratitis following pterygium removal has been reported. Here, we present a patient with Klebsiella pneumonia keratitis following pterygium surgery from Mogadishu, Somalia.…”

Section: Introductionmentioning

confidence: 99%

Multi-drug resistant Klebsiella-induced corneal ulcer following pterygium surgery: a case report

Calisir¹,

Mohamed²,

Yussuf³

2023

BMC Ophthalmol

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Background Management of pterygium is dependent on the grading of pterygium and its clinical presentation (inflamed or quiescent), and surgical excision is the final choice of treatment for the pterygium extending beyond the limbus. Infectious keratitis is one of the most commonly reported complications in recent years. To the best of our knowledge, Klebsiella keratitis after pterygium surgery has not been described in the current literature. Here, we report a patient with corneal ulcer formation following pterygium surgical excision. Case presentation A 62-year-old woman presented with complaints of pain, blurred vision, photophobia and redness in her left eye for a month. She had a history of pterygium surgical excision two months ago. Slit-lamp examination showed conjunctival congestion, a central whitish corneal ulcer with a central epithelial defect, and hypopyon. Corneal scraped sample revealed multidrug resistant (MDR) Klebsiella pneumonia and the strain was found to be sensitive to cefoxitin and ciprofloxacin. Intracameral cefuroxime (1 mg/0.1 mL) injection, fortified cefuroxime ophthalmic suspension (50 mg/mL) and moxifloxacin ophthalmic suspension (0.5%) were successfully administered to control the infection. Since residual central stromal opacification remained persistent, final visual acuity did not improve beyond finger counting at two meters. Conclusions Klebsiella keratitis is a rare and sight-threatening complication following pterygium excision. This report emphasizes the importance of close follow-up examination following pterygium surgeries.

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“…[ 3 4 5 ] There are only three published reports about AIIK following DALK due to Klebsiella pneumoniae . [ 6 7 8 ] Gram-negative bacteria are common nosocomial pathogens, and sometimes corneas from hospitalized donors are contaminated. These organisms are notorious for being multi-drug resistant (MDR).…”

mentioning

confidence: 99%

Acute interface infectious keratitis with multidrug resistant Klebsiella and Escherichia Coli following deep anterior lamellar keratoplasty

Basak

Saha

2020

Indian J Ophthalmol

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Acute interface infectious keratitis (AIIK) is a rare and devastating complication following lamellar keratoplasty. Here, we report a case of AIIK following deep anterior lamellar keratoplasty (DALK) caused by double gram-negative bacilli and required urgent therapeutic penetrating keratoplasty (TPK). Microbiology revealed co-infection with Klebsiella and E. Coli sensitive only to colistin. Donor rim culture also grew Klebsiella . TPK was successful in controlling the infection and the patient responded to topical fortified amikacin and ciprofloxacin. Since optical quality tissue was used, the patient regained 20/40 vision postoperatively. This report highlights that immediate TPK and intense antimicrobial therapy can salvage these eyes with good visual outcome.

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Extended spectrum beta-lactamase producingKlebsiella pneumoniae-related keratitis

Cited by 11 publications

References 7 publications

A case of acute postoperative keratitis after deep anterior lamellar keratoplasty by multidrug resistant Klebsiella

A case of acute postoperative keratitis after deep anterior lamellar keratoplasty by multidrug resistant Klebsiella

Multi-drug resistant Klebsiella-induced corneal ulcer following pterygium surgery: a case report

Acute interface infectious keratitis with multidrug resistant Klebsiella and Escherichia Coli following deep anterior lamellar keratoplasty

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