Extended plantar limb (modified) chevron osteotomy versus scarf osteotomy for hallux valgus correction: A randomised controlled trial

Mahadevan, Devendra; Lines, Stephen; Hepple, S.; Winson, Ian; Harries, W.

doi:10.1016/j.fas.2015.05.012

Cited by 32 publications

(30 citation statements)

References 23 publications

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“…Based on the study carried out by Mahadevan et al, 16 sample size suggested that 30 patients per group would be sufficient to detect the differences 0.66 (SD = 7) as significant at p < 0.05 with at least 80% power in this study.…”

Section: Methodsmentioning

confidence: 89%

A randomized comparison of the proximal crescentic osteotomy and rotational scarf osteotomy in the treatment of hallux valgus

Şahin¹,

Cansabuncu

Çevik

et al. 2018

Acta Orthopaedica et Traumatologica Turcica

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ObjectivesThe aim of this study was to compare clinical and radiological results of proximal crescentic osteotomy (PCO) and rotational scarf osteotomy performed in the treatment of hallux valgus.MethodsA total of 57 consecutive patients (60 feet) with symptomatic hallux valgus deformity were randomly assigned to one of two groups. The PCO group consisted of 22 women and 5 men (30 feet) and the mean age was 43(±14.5) years. The scarf group consisted of 23 women and 7 men (30 feet) and the mean age was 40.9(±12.6) years. Outcomes were assessed by using of preoperative and postoperative American Orthopaedic Foot and Ankle Society (AOFAS) scores and visual analogue scale (VAS). Weight bearing X-rays were used for radiological evaluation.ResultsThe mean AOFAS scores improved from 42(±16.2) to 66.7(±13.4) points in PCO group and from 36.2(±16.1) to 73.2(±13.5) points in scarf group. The mean pain score improved from 6.3(±1.3) to 2.4(±2) in PCO group and from 6.5(±1.9) to 2.5(±1.3) in scarf group. The mean hallux valgus angle (HVA) decreased from 38.1°(±7.1) preoperatively to 23.8°(±8.5) at postoperative first year in PCO group, and from 36.1°(±7.5) preoperatively to 22.2°(±7.5) at postoperative first year in scarf group. The mean intermetatarsal angle (IMA) decreased from 17.3°(±3.8) preoperatively to 11.8°(±3.3) at postoperative first year in PCO group, and from 16.2°(±2.6) preoperatively to 9.3°(±2.4) at postoperative first year in scarf group.When all the patients were assessed together, the relations between preoperative DMAA values and postoperative first year HVA (r = 0,327) and IMA (r = 0,399) values were positive but had low significance. The HVA and IMA values were increased in both groups at the end of the first year when compared to the postoperative sixth week values (p < 0.01 for both groups for both values).ConclusionThe PCO and the rotational scarf osteotomy in the treatment of hallux valgus deformity provides a satisfactory correction. The clinical and radiological results of both methods are similar. Especially in patients with high preoperative DMAA, an increase in the HVA and the IMA values may occur in the first postoperative year when compared to the postoperative sixth week values.Level of evidenceLevel II, therapeutic study.

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Section: Methodsmentioning

confidence: 89%

A randomized comparison of the proximal crescentic osteotomy and rotational scarf osteotomy in the treatment of hallux valgus

Şahin¹,

Cansabuncu

Çevik

et al. 2018

Acta Orthopaedica et Traumatologica Turcica

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“…Complete reduction of the IMA should result in complete repositioning of the sesamoids as well. Recent literature reports a correlation between IMA and sesamoid position in hallux deformity as well as after hallux valgus correction [ 28 , 29 ]. We believe that the IMA expresses whether the shift of the metatarsal head is sufficient.…”

Section: Discussionmentioning

confidence: 99%

Minimally invasive versus open chevron osteotomy for hallux valgus correction: a randomized controlled trial

Kaufmann¹,

Dammerer

Heyenbrock

et al. 2018

International Orthopaedics (SICOT)

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Purpose The purpose of this study was to compare a minimally invasive chevron osteotomy technique (MIS group) and the wellestablished open chevron technique (OC group) for correction of hallux valgus deformity. Methods Patients who were scheduled to undergo a hallux valgus surgery by means of a distal chevron osteotomy were randomly assigned to one of the two groups. Pre-operatively, six weeks, 12 weeks, and nine months post-operatively the following outcome parameters were determined: Visual Analog Scores (VAS) of pain, the American Orthopedic Foot and Ankle Society (AOFAS) forefoot score, radiographic outcome measures, range of motion (ROM), and patient satisfaction. Results Forty-seven cases were analyzed (25 MIS group; 22 OC group). Both operative techniques achieved significant correction of the hallux deformity. The intermetatarsal angle (IMA) improved from 15.1°to 5.8°in the OC and from 14°to 6.8°in the MIS group, whereas the hallux valgus angle (HVA) improved from 28.3°to 8.5°in the OC versus 26.4°to 6.9°in the MIS group. No significant differences were observed between the groups by any of the determined outcome parameters. Regarding patient satisfaction, statistically significant differences were found between MIS and open surgery 12 weeks post-operatively in favour of the MIS group (p = 0.022). Conclusion With the minimally invasive chevron osteotomy, radiological and clinical outcome is comparable to the open technique.

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“…Several activators were identified upstream of Ras. In addition to canonical signals from the EGF receptor (EGFR) through SHC/GRB2/SOS phosphorylation, other upstream activators contain ETV4 [108], Ras-related protein 25 (Rab25) through Src [109], RasGRP3, which naturally activates Ras via helping Ras-GDP release and that could be promoted by endothelin A receptor (ET A R) [110,111], E-selectin ligand 1 (ESL-1), which controls the rolling capacity of circulating PCa cells [112], miR-let-7c, which possibly promotes c-Myc [113][114][115], miR-407, which is secreted by cancer-associated fibroblasts that block Ras suppressor 1 (RSU-1) [116], Ras and a-factor-converting enzyme 1 (Rce1) by acting on prenylation that works on Ras anchoring [117,118], EZH2 by blocking disabled homolog 2-interacting protein (DAB2IP), a GTPase-activating protein that converts Ras-GTP to Ras-GDP, and stabilizes HIF-1α for the EMT [119][120][121], and the oxytocin receptor (OXTR) by coupling with the EGFR [122]. In contrast, to retard Ras signaling during PCa metastasis, only miR-145 [123] and phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG)/RasGAP [124] were identified.…”

Section: Ras Signalingmentioning

confidence: 99%

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis

2020

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Prostate cancer (PCa) is one of the most prevalent and malignant cancer types in men, which causes more than three-hundred thousand cancer death each year. At late stage of PCa progression, bone marrow is the most often metastatic site that constitutes almost 70% of metastatic cases of the PCa population. However, the characteristic for the osteo-philic property of PCa is still puzzling. Recent studies reported that the Wnt and Ras signaling pathways are pivotal in bone metastasis and that take parts in different cytological changes, but their crosstalk is not well studied. In this review, we focused on interactions between the Wnt and Ras signaling pathways during each stage of bone metastasis and present the fate of those interactions. This review contributes insights that can guide other researchers by unveiling more details with regard to bone metastasis and might also help in finding potential therapeutic regimens for preventing PCa bone metastasis.

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Extended plantar limb (modified) chevron osteotomy versus scarf osteotomy for hallux valgus correction: A randomised controlled trial

Cited by 32 publications

References 23 publications

A randomized comparison of the proximal crescentic osteotomy and rotational scarf osteotomy in the treatment of hallux valgus

A randomized comparison of the proximal crescentic osteotomy and rotational scarf osteotomy in the treatment of hallux valgus

Minimally invasive versus open chevron osteotomy for hallux valgus correction: a randomized controlled trial

Ras and Wnt Interaction Contribute in Prostate Cancer Bone Metastasis

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