Extended-gate FET-based enzyme sensor with ferrocenyl-alkanethiol modified gold sensing electrode

Direct detection of enzyme-catalyzed products by FET sensor with ferrocene-modified electrode

“…Recently, another type of FET sensor, an FET-based biosensor with a ferrocene-modified gold electrode, has been reported (Ishige et al, 2009). This sensor detects not protons but electrons by using mediators that transfer the produced electrons to the ferrocene molecules on the gold electrode of the FET sensor.…”

An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution

“…Interestingly, the histamine titration showed a negative shift of the transfer curve with increasing histamine concentration, while no significant change in the gate current was observed. This shift of the transfer curve could be attributed to a change of the hole concentration in the OFET conduction channel, [22][23][24] which is derived from the interfacial potential shift on the extended-gate electrode by the oxidation-state change of osmium ion. In addition, the stability of the gate current suggests that no electrochemical reaction (i.e., the electrolysis of water) was caused by applying the gate voltage.…”

A field effect transistor (FET)-based immunosensor for detection of HbA1c and Hb

“…Since it is very important for FET-based biosensors to achieve good isolation between the device and the solution, extended gate field effect transistor is frequently used (Chen et al 2003;Ishige et al 2009;Kamahori et al 2007;Kamahori et al 2008;Kim et al 2006). The extended-gate field effect transistor consists of two parts: one a sensing structure containing the sensitive membrane and the other a MOSFET structure.…”