Extended Blind End-member and Abundance Estimation with Spatial Total Variation for Hyperspectral Imaging

Cruz-Guerrero, Inés A.; Campos-Delgado, Daniel U.; Mejía-Rodríguez, Aldo R.

doi:10.1109/embc46164.2021.9629708

Cited by 2 publications

(5 citation statements)

References 19 publications

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“…While a definitive consensus is lacking, MS images (MSIs) typically feature more than three channels but fewer spectral bands than hyperspectral images [23]. In this approach, the data acquired through the different bands represent a spectral signature of tissue located in each pixel [21], [24], [25]. Next, the spectral signature can be analyzed to infere information, which can be associated with the pixel chemical composition [6], [21].…”

Section: Introductionmentioning

confidence: 99%

“…However, when dealing with MS imaging, a single pixel rarely contains the pure spectrum of a single component. Instead, it usually represents a mixture of spectral signatures from various targets, along with noise [24]. As a result, unmixing methods are utilized to discern these components.…”

Section: Introductionmentioning

confidence: 99%

“…As a result, unmixing methods are utilized to discern these components. Typically, these methods rely on a linear mixture model, and thus, the task of collectively estimating this information within a dataset is referred to as blind linear unmixing (BLU) analysis [22], [24]- [26]. One of the basic approaches for BLU is principal component analysis (PCA), commonly used in dimensional reduction.…”

Section: Introductionmentioning

confidence: 99%

“…Consequently, we explore an alternative BLU technique: extended blind endmember and abundance extraction (EBEAE) [25]. This method has been applied to hyperspectral imaging for cancer detection [24], to multispectral fluorescence lifetime imaging for oral cancer evaluation, and optical coherence tomography for macrophages identification in artery samples [25], [26]. EBEAE is considered a constrained methodology in which the spectral information could be associated with the optical properties of the SBP parameters [22], [25], [26].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Contactless Skin Blood Perfusion Imaging via Multispectral Information, Spectral Unmixing and Multivariable Regression

Granados-Castro,

Gutierrez-Navarro,

Mejia-Rodriguez

et al. 2024

IEEE Open J. Signal Process.

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Noninvasive methods for assessing in-vivo skin blood perfusion parameters, such as hemoglobin oxygenation, are crucial for diagnosing and monitoring microvascular diseases. This approach is particularly beneficial for patients with compromised skin, where standard contact-based clinical devices are inappropriate. For this goal, we propose the analysis of multimodal data from an occlusion protocol applied to 18 healthy participants, which includes multispectral imaging of the whole hand and reference photoplethysmography information from the thumb. Multispectral data analysis was conducted using two different blind linear unmixing methods: principal component analysis (PCA), and extended blind endmember and abundance extraction (EBEAE). Perfusion maps for oxygenated and deoxygenated hemoglobin changes in the hand were generated using linear multivariable regression models based on the unmixing methods. Our results showed high accuracy, with R 2 -adjusted values, up to 0.90±0.08. Further analysis revealed that using more than four characteristic components during spectral unmixing did not improve the fit of the model. Bhattacharyya distance results showed that the fitted models with EBEAE were more sensitive to hemoglobin changes during occlusion stages, up to four times higher than PCA. Our study concludes that multispectral imaging with EBEAE is effective in quantifying changes in oxygenated hemoglobin levels, especially when using 3 to 4 characteristic components. Our proposed method holds promise for the noninvasive diagnosis and monitoring of superficial microvascular alterations across extensive anatomical regions.INDEX TERMS skin blood perfusion, hemoglobin, multispectral imaging, photoplethysmography, spectral unmixing.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Contactless Skin Blood Perfusion Imaging via Multispectral Information, Spectral Unmixing and Multivariable Regression

Granados-Castro,

Gutierrez-Navarro,

Mejia-Rodriguez

et al. 2024

IEEE Open J. Signal Process.

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“…We employ two regularization techniques to achieve this: the total-variation (TV) regularizer and the Plug-and-Play (PnP) prior. The TV regularizer is applied to the reconstructed image to incorporate spatial and spectral information through pixel connections in the unmixing process [31,32]. On the other hand, the PnP technique utilizes state-of-the-art denoisers to tackle linear inverse problems in various hyperspectral image processing tasks [33][34][35][36][37].…”

Section: Introductionmentioning

confidence: 99%

Sterility of Aedes albopictus by X-ray Irradiation as an Alternative to γ-ray Irradiation for the Sterile Insect Technique

Wang

Ren

et al. 2023

Pathogens

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The mosquito Aedes albopictus can transmit various arboviral diseases, posing a severe threat to human health. As an environmentally friendly method, sterile insect technology (SIT) is considered an alternative to traditional methods such as chemical pesticides to control Ae. albopictus. In SIT, the sterility of male mosquitoes can be achieved by γ-ray or X-ray radiation. Compared with γ-rays, X-rays are easier to obtain, cheaper, and less harmful. However, there is a lack of comparative assessment of these two types of radiation for SIT under the same controlled conditions. Here, we compared the effects of X-ray and γ-ray radiation on the sterility of Ae. albopictus males under laboratory-controlled conditions. Neither type of radiation affected the number of eggs but significantly reduced the survival time and hatch rate. The same dose of γ-rays caused a higher sterility effect on males than X-rays but had a more significant impact on survival. However, X-rays could achieve the same sterility effect as γ-rays by increasing the radiation dose. For example, X-rays of 60 Gy induced 99% sterility, similar to γ-rays of 40 Gy. In the test of male mating competitiveness, the induced sterility and the male mating competitiveness index were also identical at the same release ratio (sterile males/fertile males). At a release ratio of 7:1, nearly 80% of eggs failed to hatch. Sterile males produced by X-ray and γ-ray radiation had similar male competitiveness in competition with field males. In conclusion, a higher dose of X-rays is required to achieve the same sterility effect, compared to γ-rays. When γ-rays are not readily available, high-dose X-rays can be used instead. This study provides data supporting the selection of more suitable radiation for the field release of sterile male mosquitoes.

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Extended Blind End-member and Abundance Estimation with Spatial Total Variation for Hyperspectral Imaging

Cited by 2 publications

References 19 publications

Contactless Skin Blood Perfusion Imaging via Multispectral Information, Spectral Unmixing and Multivariable Regression

Contactless Skin Blood Perfusion Imaging via Multispectral Information, Spectral Unmixing and Multivariable Regression

Sterility of Aedes albopictus by X-ray Irradiation as an Alternative to γ-ray Irradiation for the Sterile Insect Technique

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