Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases
Dohee Lee,
Sanggu Kim,
Yoonhoi Koo
et al.
Abstract:Vitamin D plays a role in anti-inflammatory processes, and the alteration of its metabolism is associated with the inflammatory processes of pancreatitis. This study was performed to evaluate the expression of the vitamin D receptor (VDR) and the two major enzymes that regulate vitamin D metabolism, 1α-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24A1), in the canine pancreas and to compare their degrees of immunoreactivity between normal and inflamed pancreases. Five normal and inflamed pancreatic tissues eac… Show more
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