Abstract:Introduction: The aim was to investigate the expression of TLR2 and TLR5 in the distal ileum of mice with obstructive jaundice (OJ) and their role in intestinal mucosal injury. Material and methods: A total of 100 male C57BL/6J mice were randomly assigned to two groups: (I) sham operation (SH); (II) bile duct ligation (BDL). The mice were respectively sacrificed before operation and on the 1 st , 3 rd , 5 th and 7 th days after operation to collect specimens. Various indicators were detected by PCR, immunohist… Show more
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