Expression of the mRNA for two isoforms of neural plakophilin-related arm-repeat protein/δ-catenin in rodent neurons and glial cells

Increased expression of δ-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer

“…Examination of available human EST data bank also revealed d-catenin messenger RNA (mRNA) sequences in kidney, ovarian, brain, breast, and esophageal tumors [17]. These observations are consistent with the finding that d-catenin mRNA can be detected in cultures of SH-SY5Y human neuroblastoma cells, as well as the P19 human embryonal carcinoma stem cells of ependymal origin [7,18]. Together, these findings suggest a possible d-catenin association with cancer.…”

Brain armadillo protein δ‐catenin interacts with Abl tyrosine kinase and modulates cellular morphogenesis in response to growth factors

“…Studies are currently underway to identify this regulatory event in neuronal differentiation, in which ␦-catenin may have a role, as recently suggested by the report correlating ␦-catenin mRNA expression with P19 embryonal stem cell differentiation (Kawamura et al, 1999).…”

Xenopus δ-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases

“…Furthermore, alignment of all sequenced cDNAs revealed three sequence elements (A, B and C) present in Xenopus -catenin that have not been reported in mammals. Conversely, mouse -catenin contains a splicing variant (D) that we have not yet identified in Xenopus (Kawamura et al, 1999). The A, B and C variants are likely to arise from alternative splicing, because these sequences occur precisely within predicted exon junctions (see also below).…”