Expression of the mouse ren-2 gene in the small intestine is regulated by food intake

Zhao, Yi; Peters, J; Ganten, Detlev; Bäder, Michael

doi:10.1007/bf00384342

Cited by 5 publications

(1 citation statement)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1989;Morishita et al 1991), but is stimulated by AII, possibly via a novel action involving a nuclear receptor for this peptide (Eggena et al 1993). The intestine also contains renin mRNA (Seo et al 199 I), which is suppressed by starvation (Zhao et al 1993). Another site in which renin mRNA has been detected is the eye, particularly in the ciliary body, iris and retina, and possibly in blood vessels (Brandt et al 1994).…”

Section: Other Tissuesmentioning

confidence: 99%

Some Physiological Outcomes of Renin Gene Studies

Morris

1995

Clin Exp Pharma Physio

View full text Add to dashboard Cite

1. The cloning of the renin gene has permitted studies of its physiological regulation, extrarenal expression and role in disease. 2. Marked modulation of renin mRNA concentration is seen in adrenal, heart and hypothalamus in response to sodium depletion and inhibition of AII formation, as well as in models of renal and genetic hypertension in the rat. 3. One important outcome of studies of the promoter has been the discovery of a cyclic AMP-responsive sequence. 4. Sequence variations have been detected in or near the renin gene and have been used as markers in studies of its role in cardiovascular disease aetiology. 5. In conclusion, molecular biology has, in the past decade, made a significant contribution to the understanding of renin physiology and pathophysiology.

show abstract

Section: Other Tissuesmentioning

confidence: 99%

Some Physiological Outcomes of Renin Gene Studies

Morris

1995

Clin Exp Pharma Physio

View full text Add to dashboard Cite

show abstract

Renin

Morris¹

2000

Comprehensive Physiology

View full text Add to dashboard Cite

The sections in this article are: The Renin Paper A blood pressure‐raising substance is formed in the kidneys and passed into the blood Time course of the pressure elevation following injection of renin Analysis of the mechanism underlying the pressure rise Renin Release Regulation Renin Gene: Structure and Control Background Renin Gene Structure Renin Promoter Structure Renin Promoter Control Transcription Factors Renin Messenger RNA Synthesis and Activation Biosynthesis of Prorenin Processing of Prorenin Structure of Renin Binding Protein(s) of Renin Genetic Studies Studies in Rats Studies in Humans Transgenic Mice and Rats Human Gene in Mice Renin Promoter–Simian Virus 40 T Antigen Transgenic Mice Human Promoter Transgenic Mice Ren‐2 Hypertensive Transgenic Rats Model of Malignant Hypertension Renin and Angiotensinogen Transgenic Mice and Rats Knockouts Summary and Challenges

show abstract

Endocrine Control of Sodium Balance

Fray

2000

Comprehensive Physiology

View full text Add to dashboard Cite

The sections in this article are: Components of the Renin–Angiotensin System Prorenin/Renin Renin Gene Structure, Evolutionary Function, and Regulation Biosynthesis and Chemiosmotic Activation Tissue Distribution in Health and Disease Kidney Heart and Blood Vessels Adrenal Brain Eye, Liver, and Intestine Ovary, Uterus, Testis, and Sex Accessory and Subcutaneous Tissue Submandibular Gland Spontaneously Hypertensive Rat Renal Hypertensive Rat Growth Retardation Relative Renin Plasma Levels and Suggestive Meaning Angiotensinogen Biochemical Properties Tissue Expression and In Situ Regulation Factors Regulating Release Mechanism of Action and Physiological Effects Summary and Challenges Angiotensin I–Converting Enzyme Molecular Structure and Regulation Active Sites and Catalytic Properties Tissue Distribution Summary and Challenges Angiotensin Peptides Aldosterone Biosynthesis and Metabolism Secretion and Its Regulation Angiotensin II Potassium Corticotropin and Other Proopiomelanocortin Peptides Various Stimulators of Aldosterone Secretion Various Inhibitors of Aldosterone Secretion Cellular Actions Disorders of Aldosterone Secretion Systemic Regulation of Sodium Volume Homeostasis Regulation of Sodium Volume Homeostasis Integrative Regulation of Sodium Volume and Blood Pressure Homeostasis Integrative Regulation of Sodium and Potassium Homeostasis Integrative Regulation by Potassium and Hydrogen in Volume Homeostasis Polyendocrinopathy Type III: Systemic Dysregulation of Sodium Volume Homeostasis Primary and Pseudoprimary Aldosteronism Secondary Aldosteronism: Renin Tumors and Edematous States High‐Renin States and Low‐Renin Syndromes Summary and Challenges: Defining Functions and Processing Strategies of Renin–Angiotensin System Molecules

show abstract

Expression of the mouse ren-2 gene in the small intestine is regulated by food intake

Cited by 5 publications

References 39 publications

Some Physiological Outcomes of Renin Gene Studies

Some Physiological Outcomes of Renin Gene Studies

Renin

Endocrine Control of Sodium Balance

Contact Info

Product

Resources

About