Expression of mPGES1 and p16 in feline and human oral squamous cell carcinoma: A comparative oncology approach
Walaa Hamed Shaker Nasry,
Kathleen Jones,
Juan Carlos Rodriguez‐Lecompte
et al.
Abstract:Comparative cancer studies help us determine if discoveries in one species apply to another. Feline and human oral squamous cell carcinoma (FOSCC and HOSCC) are invasive tumours in which inflammation and abnormal p16 expression are reported. Immunohistochemistry was used to determine the expression of p16 and microsomal prostaglandin E2 synthase 1 (mPGES1) in 42 HOSCC and 45 FOSCC samples with known expression of cyclooxygenase 2 (COX2) and cluster of differentiation 147 (CD147). High p16 expression was more c… Show more
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