“…Primary cilium was identified as a key coordinator of signaling during organogenesis, and it had been shown that the primary cilium participated in receiving signals from Notch, PDGFRα, FGF, Wnt, and Hedgehog pathways (Wainwright et al, 2014). Primary cilia-related genes are present in different cell types of gonads and may be important for the differentiation of gonad cells and sex differentiation of gonads in mammals (Piprek et al, 2019). However, the role of primary cilium in the sex determination and gonadal differentiation in fish is completely unknown.…”