Expression of mRNA for nutrient transporters in the
gastrointestinal tract before and after weaning

Hayashi, Hideaki; Yonezawa, Tomo; Kanetani, T.; Katoh, Keiko; Obara, Yoshiaki

doi:10.22358/jafs/73948/2004

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…It was demonstrated that the weaning of calves and goats reduces the expression of the sodium-dependent glucose transporter 1 and CD36 (a fatty acid transporter; Hayashi et al, 2004Hayashi et al, , 2005 as well as leptin (Yonekura et al, 2002) in the gastrointestinal tract. The salivary secretion rate (Sasaki, 1968) and the activity of carbonic anhydrase in the parotid gland (Kitade et al, 2002) in calves are increased around weaning.…”

Section: Introductionmentioning

confidence: 99%

Developmental Changes in the Kinetics of Glucose and Urea in Holstein Calves

Hayashi

Kawai

Nonaka

et al. 2006

Journal of Dairy Science

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Because weaning is the point when the nutrient composition of feed changes for the neonatal ruminant, the present experiment was conducted to assess the developmental changes in the kinetics of glucose and urea over this period, using stable isotopes of glucose and urea, at 4, 13, and 24 wk in calves. Plasma concentrations of nonesterified fatty acids, amino-N, urea-N, and insulin-like growth factor-I increased, but that of growth hormone decreased with age. The plasma glucose concentration increased at 13 wk of age and thereafter decreased at 24 wk of age. The glucose irreversible loss and recycling rates were significantly higher at 4 wk of age than at 13 and 24 wk of age. On the other hand, the irreversible loss and recycling rates of urea, as well as the urea pool size, were higher at 24 wk of age than at 4 and 13 wk. It is concluded that weaning at 6 wk is the pivotal time for the alteration of glucose kinetics. However, the aging process, but not weaning, is important for changes in the kinetics of urea in calves.

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Section: Introductionmentioning

confidence: 99%

Developmental Changes in the Kinetics of Glucose and Urea in Holstein Calves

Hayashi

Kawai

Nonaka

et al. 2006

Journal of Dairy Science

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Responses induced by arginine-vasopressin injection in the plasma concentrations of adrenocorticotropic hormone, cortisol, growth hormone and metabolites around weaning time in goats

Katoh¹,

Yoshida²,

Kobayashi³

et al. 2005

Journal of Endocrinology

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In order to assess the biological significance of weaning and water deprivation on the control of plasma concentrations of adrenocorticotropic hormone (ACTH), cortisol, growth hormone (GH) and metabolites in response to stimulation with arginine-vasopressin (AVP) and corticotropin-releasing hormone (CRH), we carried out three experiments in which male goats before and after weaning were intravenously injected with AVP or CRH alone, or in combination with each other. In experiment 1, 17-week-old (post-weaning) goats were intravenously injected with AVP or CRH alone at the doses of 0·1, 0·3 and 1·0 nmol/kg body weight (BW). The AVP injection significantly and dose dependently increased plasma levels of ACTH, cortisol, GH and metabolites, whereas the injection with CRH did not cause significant increases in the levels of these parameters. In experiment 2, 4-weekold (pre-weaning) and 13-week-old (post-weaning) goats were injected with either AVP or CRH alone, followed by a combined injection of both secretagogues at a dose of 0·3 nmol/kg BW. Although the basal levels of the hormones and metabolites, with the exception of glucose, were greater in the 4-week-old goats, the hormone responses induced by stimulation with AVP were weaker than those induced in 13-week-old goats. Additionally, there were no responses in any hormone patterns to CRH stimulation in 4-week-old goats. In experiment 3, 13-week-old goats were injected with CRH alone followed by injection with AVP for two consecutive days of water deprivation. The animals were subjected to withdrawal of up to 20% of the total blood volume and water deprivation for up to 28 h. However, no significant differences in plasma ACTH, cortisol or GH levels were observed between days 1 and 2. Based on these results, we concluded that: (1) AVP is a more potent stimulant than CRH in terms of its ability to induce increases in plasma levels of ACTH, cortisol and GH; (2) the role of AVP as a secretagogue of hypothalamus-pituitary-adrenal hormones is strengthened, whereas the ineffective role of CRH remains unaltered, by weaning; (3) acute stress such as massive withdrawal of blood volume and subjection to water deprivation may not be sufficient burdens to alter stress-related hormone levels in young goats.

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Expression of mRNA for nutrient transporters in the gastrointestinal tract before and after weaning

Cited by 2 publications

References 4 publications

Developmental Changes in the Kinetics of Glucose and Urea in Holstein Calves

Developmental Changes in the Kinetics of Glucose and Urea in Holstein Calves

Responses induced by arginine-vasopressin injection in the plasma concentrations of adrenocorticotropic hormone, cortisol, growth hormone and metabolites around weaning time in goats

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