Abstract:Summary statement: Expression of Lamin Dm0 or Kugelkern curb stem cell proliferation by suppression of Jak/Stat signalling.
AbstractThe nuclear lamina is involved in numerous cellular functions, such as gene expression, nuclear organization, nuclear stability, and cell proliferation. The mechanism underlying the involvement of lamina is often not clear, especially in physiological contexts. Here we investigate how the farnesylated lamina proteins Lamin Dm0 and Kugelkern are linked to proliferation control of i… Show more
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