“…In chromaffin cells, AChE has been reported to exist in the cell membrane and in different subcellular organelles (7,49). Bovine chromaffin cells also secrete AChE upon depolarizing stimulation and in the presence of Ca 2ϩ , suggesting an exocytotic mechanism, and thus the presence of the enzyme in some kind of secretory vesicle or endosome (51,58).…”