Expression of CD44highCD24Low cells, SOX2, and STAT3 transcription factors on peripheral blood and tumor tissue of penile squamous cell carcinoma
Felipe Dubourcq de Barros,
Gustavo Cardoso Guimarães,
Mário Rino Martins
et al.
Abstract:BackgroundPenile cancer is high in some underdeveloped countries. Signal transducer and activator of transcription 3 (STAT3) and CD44, CD24, and SOX2+ are known to be markers of diagnosis and prognosis in other cancers, but without studies in penile cancer.MethodsA cross‐sectional study was conducted at the Hospital de Cancer de Pernambuco from March 2015 to December 2017. We performed SOX2, STAT3, CD24, and CD44 analyses in blood and tumor tissue by flow cytometry.ResultsHigh levels of CD44highCD24low, CD44hi… Show more
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