2008
DOI: 10.1111/j.1600-6143.2008.02232.x
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Expression of B Cell and Immunoglobulin Transcripts Is a Feature of Inflammation in Late Allografts

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Cited by 88 publications
(90 citation statements)
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References 37 publications
(78 reference statements)
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“…(5). The molecular phenotype is reviewed in a companion paper (6) but the lessons from the molecular studies are incorporated here to propose an integrated approach to interpreting biopsy findings and outcomes, (13), mast cell transcripts (14) and FOXP3 mRNA (15). (22).…”
Section: Much Has Changed Since 2002 the Term Chronic Allograft Nephmentioning
confidence: 99%
“…(5). The molecular phenotype is reviewed in a companion paper (6) but the lessons from the molecular studies are incorporated here to propose an integrated approach to interpreting biopsy findings and outcomes, (13), mast cell transcripts (14) and FOXP3 mRNA (15). (22).…”
Section: Much Has Changed Since 2002 the Term Chronic Allograft Nephmentioning
confidence: 99%
“…(15,(26)(27)(28)(29)(30). Both protocol and indication biopsies beyond 6 months posttransplant often manifest an increase in B-cell nodules as well as scarring (15,22,26,28 g. IL4, IL6, IL13), potentially through collagen production and fibroblast proliferation (10,33,34 …”
Section: Infiltrates and Scarringmentioning
confidence: 99%
“…We previously reported that fibrosis in human kidney transplants was associated with transcripts expressed in certain inflammatory cells: mast cell transcripts (MCATs) such as carboxypeptidase 3 (CPA3) (26) and immunoglobulin transcripts (IGTs) representing plasma cells (27). Such transcripts do not correlate with TCMR or ABMR.…”
Section: Funding Canada Foundation For Innovation and Genome Canadamentioning
confidence: 99%